Disseminated cryptococcosis in an immunocompetent farmer: A rare case report
Cryptococcosis is an opportunistic fungal infection commonly occurring amongst immunocompromised individuals. However, in rare cases it can affect immunocompetent individuals particularly those with exposure to fungal reservoirs in environment. We report a 32-year-old immunocompetent male farmer who...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250925000976 |
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| author | Sunil Gaikwad Monika Pujari Harsh Joshi Shubhada Kulkarni Divya Patel Sanjay Pujari |
| author_facet | Sunil Gaikwad Monika Pujari Harsh Joshi Shubhada Kulkarni Divya Patel Sanjay Pujari |
| author_sort | Sunil Gaikwad |
| collection | DOAJ |
| description | Cryptococcosis is an opportunistic fungal infection commonly occurring amongst immunocompromised individuals. However, in rare cases it can affect immunocompetent individuals particularly those with exposure to fungal reservoirs in environment. We report a 32-year-old immunocompetent male farmer who was diagnosed with disseminated cryptococcosis. He initially presented with prolonged cough, exertional dyspnoea and weight loss and later developed nodulo-ulcerative skin lesion and central nervous system cryptococcomas. The diagnosis was confirmed by histopathology and cryptococcal antigen testing. He was treated with liposomal amphotericin B and flucytosine, followed by maintenance fluconazole therapy. This case-report highlights the importance of keeping a high index of suspicion for disseminated cryptococcosis even in immunocompetent individuals. |
| format | Article |
| id | doaj-art-d53d9acbd84946c68b0ecb258e739015 |
| institution | OA Journals |
| issn | 2214-2509 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj-art-d53d9acbd84946c68b0ecb258e7390152025-08-20T02:05:17ZengElsevierIDCases2214-25092025-01-0140e0224110.1016/j.idcr.2025.e02241Disseminated cryptococcosis in an immunocompetent farmer: A rare case reportSunil Gaikwad0Monika Pujari1Harsh Joshi2Shubhada Kulkarni3Divya Patel4Sanjay Pujari5Institute of Infectious Diseases, Pune, India; Poona Hospital and Research Centre, Pune, India; Correspondence to: Institute of Infectious Diseases, Business Court, Mukundnagar, Pune, Maharashtra 411037, India.Poona Hospital and Research Centre, Pune, IndiaPoona Hospital and Research Centre, Pune, IndiaPoona Hospital and Research Centre, Pune, IndiaPoona Hospital and Research Centre, Pune, IndiaInstitute of Infectious Diseases, Pune, India; Poona Hospital and Research Centre, Pune, IndiaCryptococcosis is an opportunistic fungal infection commonly occurring amongst immunocompromised individuals. However, in rare cases it can affect immunocompetent individuals particularly those with exposure to fungal reservoirs in environment. We report a 32-year-old immunocompetent male farmer who was diagnosed with disseminated cryptococcosis. He initially presented with prolonged cough, exertional dyspnoea and weight loss and later developed nodulo-ulcerative skin lesion and central nervous system cryptococcomas. The diagnosis was confirmed by histopathology and cryptococcal antigen testing. He was treated with liposomal amphotericin B and flucytosine, followed by maintenance fluconazole therapy. This case-report highlights the importance of keeping a high index of suspicion for disseminated cryptococcosis even in immunocompetent individuals.http://www.sciencedirect.com/science/article/pii/S2214250925000976CryptococcosisImmunocompetentDisseminatedEnvironmental exposure |
| spellingShingle | Sunil Gaikwad Monika Pujari Harsh Joshi Shubhada Kulkarni Divya Patel Sanjay Pujari Disseminated cryptococcosis in an immunocompetent farmer: A rare case report IDCases Cryptococcosis Immunocompetent Disseminated Environmental exposure |
| title | Disseminated cryptococcosis in an immunocompetent farmer: A rare case report |
| title_full | Disseminated cryptococcosis in an immunocompetent farmer: A rare case report |
| title_fullStr | Disseminated cryptococcosis in an immunocompetent farmer: A rare case report |
| title_full_unstemmed | Disseminated cryptococcosis in an immunocompetent farmer: A rare case report |
| title_short | Disseminated cryptococcosis in an immunocompetent farmer: A rare case report |
| title_sort | disseminated cryptococcosis in an immunocompetent farmer a rare case report |
| topic | Cryptococcosis Immunocompetent Disseminated Environmental exposure |
| url | http://www.sciencedirect.com/science/article/pii/S2214250925000976 |
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