The influence of the geroprotective cytokine on the transcriptome of young and senescent mesenchymal stem cells

The influence of the geroprotective cytokine on the transcriptome of young and senescent mesenchymal stem cells

Abstract Objectives Increasing longevity and the growing elderly population necessitate a deeper understanding of aging mechanisms to prolong productive life and improve treatments for age-related diseases linked with cellular senescence. Mesenchymal stem cells (MSCs) are crucial for maintaining tis...

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Bibliographic Details
Main Authors: Liya G. Kondratyeva, Diana K. Matveeva, Maria I. Ezdakova, Marina V. Utkina, Andrey Yu. Ratushnyy
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Research Notes
Subjects:
RNA-sequencing
Transcriptome
Mesenchymal stem cells
MSCs
Cell senescence
GDF11
Online Access:https://doi.org/10.1186/s13104-025-07262-8
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