Local therapy in the postoperative management of patients with lower limb varicose vein disease
Introduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essent...
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Remedium Group LTD
2024-05-01
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| Series: | Амбулаторная хирургия |
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| Online Access: | https://www.a-surgeon.ru/jour/article/view/432 |
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| author | I. N. Mokhamad |
| author_facet | I. N. Mokhamad |
| author_sort | I. N. Mokhamad |
| collection | DOAJ |
| description | Introduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essential phospholipids in the postoperative administration of patients after endovenous laser coagulation.Materials and methods. A complex treatment of 53 patients with varicose veins of the lower extremities of classes C2-C3 according to the CEAP nomenclature was carried out. Patients were divided into 2 statically homogeneous groups with an equal number. All patients underwent endovenous laser obliteration of the trunk of the great saphenous vein in combination with miniphlebectomy of tributaries on the thigh and lower leg.Results. In both groups, the largest number were patients with incompetence of the GSV trunk up to the border in /3 and c/3 of the lower leg, with further discharge along the tributaries of the GSV along the medial surface of the lower leg. The failure of the GSV trunk to the level of the knee joint gap was accompanied by the presence of varicose-transformed tributaries along the anterior surface of the thigh, in the area of the knee joint. The addition of Detragel led to the relief of phlebitis and hematomas, a pronounced decrease in pain and edematous syndrome.Discussion. Transdermal drug delivery has great promise as an alternative to oral and intravenous treatment, especially for patients suffering from chronic diseases. The three-component composition allows you to influence all parts of the pathogenesis of the disease.Conclusion. The data obtained on the use of local gel therapy based on escin, heparin and essential phospholipids after EVLO of the GSV indicate the need for local therapy to improve the quality of life of patients, their rapid rehabilitation and improve immediate and long-term results. |
| format | Article |
| id | doaj-art-d531625c3d5f4bc6b84cce54861c0e50 |
| institution | OA Journals |
| issn | 2712-8741 2782-2591 |
| language | Russian |
| publishDate | 2024-05-01 |
| publisher | Remedium Group LTD |
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| series | Амбулаторная хирургия |
| spelling | doaj-art-d531625c3d5f4bc6b84cce54861c0e502025-08-20T02:17:37ZrusRemedium Group LTDАмбулаторная хирургия2712-87412782-25912024-05-0121113013410.21518/akh2024-008351Local therapy in the postoperative management of patients with lower limb varicose vein diseaseI. N. Mokhamad0VenArt Vascular Treatment CenterIntroduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essential phospholipids in the postoperative administration of patients after endovenous laser coagulation.Materials and methods. A complex treatment of 53 patients with varicose veins of the lower extremities of classes C2-C3 according to the CEAP nomenclature was carried out. Patients were divided into 2 statically homogeneous groups with an equal number. All patients underwent endovenous laser obliteration of the trunk of the great saphenous vein in combination with miniphlebectomy of tributaries on the thigh and lower leg.Results. In both groups, the largest number were patients with incompetence of the GSV trunk up to the border in /3 and c/3 of the lower leg, with further discharge along the tributaries of the GSV along the medial surface of the lower leg. The failure of the GSV trunk to the level of the knee joint gap was accompanied by the presence of varicose-transformed tributaries along the anterior surface of the thigh, in the area of the knee joint. The addition of Detragel led to the relief of phlebitis and hematomas, a pronounced decrease in pain and edematous syndrome.Discussion. Transdermal drug delivery has great promise as an alternative to oral and intravenous treatment, especially for patients suffering from chronic diseases. The three-component composition allows you to influence all parts of the pathogenesis of the disease.Conclusion. The data obtained on the use of local gel therapy based on escin, heparin and essential phospholipids after EVLO of the GSV indicate the need for local therapy to improve the quality of life of patients, their rapid rehabilitation and improve immediate and long-term results.https://www.a-surgeon.ru/jour/article/view/432varicose veins of the lower extremitiesendovenous laser ablationdetragelminiphlebectomytopical therapy |
| spellingShingle | I. N. Mokhamad Local therapy in the postoperative management of patients with lower limb varicose vein disease Амбулаторная хирургия varicose veins of the lower extremities endovenous laser ablation detragel miniphlebectomy topical therapy |
| title | Local therapy in the postoperative management of patients with lower limb varicose vein disease |
| title_full | Local therapy in the postoperative management of patients with lower limb varicose vein disease |
| title_fullStr | Local therapy in the postoperative management of patients with lower limb varicose vein disease |
| title_full_unstemmed | Local therapy in the postoperative management of patients with lower limb varicose vein disease |
| title_short | Local therapy in the postoperative management of patients with lower limb varicose vein disease |
| title_sort | local therapy in the postoperative management of patients with lower limb varicose vein disease |
| topic | varicose veins of the lower extremities endovenous laser ablation detragel miniphlebectomy topical therapy |
| url | https://www.a-surgeon.ru/jour/article/view/432 |
| work_keys_str_mv | AT inmokhamad localtherapyinthepostoperativemanagementofpatientswithlowerlimbvaricoseveindisease |