Male-specific lethal 1 (MSL1) promotes Erastin-induced ferroptosis in colon cancer cells by regulating the KCTD12-SLC7A11 axis

Abstract MSL1, a scaffold protein of the MSL histone acetyltransferase complex, is crucial for its structural integrity and enzymatic activity. While MSL1 is highly expressed in various tumors, its role in tumor progression and cell death remains unclear. Here, we provide evidence of a negative regu...

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Bibliographic Details
Main Authors: Lifu Luo, Qingzhi Zhao, Xueli Cui, Shijiao Dong, Yong Wang, Nan Jiang, Chengyu Cai, Jingji Jin, Bing Liang
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07555-7
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