THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION
Objective: investigation of gender features and their role in progression and treatment of acute myocardial infarction (MI).Materials and methods. 244 patients aged 30–85 (mean age 61.2 ± 12.3) with MI were included in this study. They were divided into 2 groups depending on their gender: the 1st gr...
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2017-01-01
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| author | T. M. Murataliev V. K. Zventsova Yu. N. Neklyudova Z. T. Radzhapova S. Yu. Mukhtarenko |
| author_facet | T. M. Murataliev V. K. Zventsova Yu. N. Neklyudova Z. T. Radzhapova S. Yu. Mukhtarenko |
| author_sort | T. M. Murataliev |
| collection | DOAJ |
| description | Objective: investigation of gender features and their role in progression and treatment of acute myocardial infarction (MI).Materials and methods. 244 patients aged 30–85 (mean age 61.2 ± 12.3) with MI were included in this study. They were divided into 2 groups depending on their gender: the 1st group was comprised of 80 (32.8 %) women, the 2nd group – of 164 (67.2 %) men. We evaluated patients’ demographic data, diagnosis and its complications, comorbidities, medical history and risk factors (RF) of coronary heart disease (CHD), in-patient therapeutic activities, in-hospital mortality rate, and 12-month mortality rate after MI.Results. In women MI was significantly more often associated with arterial hypertension (p < 0,01), diabetes mellitus (p < 0,05) and obesity (p < 0,05); prevalence of smoking was higher among men (p < 0,01).The most common MI complication in both groups was acute heart failure (HF), registered in 53.7 % of females and 55.5 % of males (relative risk (RR) 0.96; 95 % confidence interval (CI) 0.75–1.23; p > 0,05), however severe (class III–IV) heart failure was more common in female population (31.2 % vs 23.7 %; RR 1.31; 95 % CI 0.85–2.01; p > 0.05).Mortality rate was higher in women than in men (27.5 % vs 15.2 %; RR 1.8; 95 % CI 1.08–2.99; р < 0,05), the same trend was observed both for their in-hospital mortality (18.7 % vs 9.1 %; RR 2.05; 95 % CI 1.05–3.98; р < 0,05) and post-discharge mortality (8.7 % vs 6.1 %; RR 1.43; 95 % CI 0.56–3.63; р > 0.05). During the first 6 months after MI we found a tendency of higher mortality rate in females than in males (6.2 % vs 1.8 %; RR 3.41; 95 % CI 0.83–13.9; p > 0.05), but after 6–12 months after discharge males tended to have higher mortality than females (4.3 % vs 2.5 %; RR 0.58; 95 % CI 0.12–2.75; p > 0.05).Conclusion. The most important risk factors for MI in females are diabetes mellitus, arterial hypertension and obesity. MI in women is associated with severe HF development; their immediate prognosis and disease outcome is usually less favorable, than in men. |
| format | Article |
| id | doaj-art-d5176ff74dde4998a67634a22df8b741 |
| institution | Kabale University |
| issn | 1818-8338 |
| language | Russian |
| publishDate | 2017-01-01 |
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| spelling | doaj-art-d5176ff74dde4998a67634a22df8b7412025-08-20T03:45:04ZrusABV-pressKlinicist1818-83382017-01-01103586310.17650/1818-8338-2016-10-3-58-63254THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTIONT. M. Murataliev0V. K. Zventsova1Yu. N. Neklyudova2Z. T. Radzhapova3S. Yu. Mukhtarenko4Akad. M. Mirrakhimov National Center of Cardiology and TherapyAkad. M. Mirrakhimov National Center of Cardiology and TherapyAkad. M. Mirrakhimov National Center of Cardiology and TherapyThe first Russian President B.N. Eltzyn Kyrgyz-Russian Slavic UniversityAkad. M. Mirrakhimov National Center of Cardiology and TherapyObjective: investigation of gender features and their role in progression and treatment of acute myocardial infarction (MI).Materials and methods. 244 patients aged 30–85 (mean age 61.2 ± 12.3) with MI were included in this study. They were divided into 2 groups depending on their gender: the 1st group was comprised of 80 (32.8 %) women, the 2nd group – of 164 (67.2 %) men. We evaluated patients’ demographic data, diagnosis and its complications, comorbidities, medical history and risk factors (RF) of coronary heart disease (CHD), in-patient therapeutic activities, in-hospital mortality rate, and 12-month mortality rate after MI.Results. In women MI was significantly more often associated with arterial hypertension (p < 0,01), diabetes mellitus (p < 0,05) and obesity (p < 0,05); prevalence of smoking was higher among men (p < 0,01).The most common MI complication in both groups was acute heart failure (HF), registered in 53.7 % of females and 55.5 % of males (relative risk (RR) 0.96; 95 % confidence interval (CI) 0.75–1.23; p > 0,05), however severe (class III–IV) heart failure was more common in female population (31.2 % vs 23.7 %; RR 1.31; 95 % CI 0.85–2.01; p > 0.05).Mortality rate was higher in women than in men (27.5 % vs 15.2 %; RR 1.8; 95 % CI 1.08–2.99; р < 0,05), the same trend was observed both for their in-hospital mortality (18.7 % vs 9.1 %; RR 2.05; 95 % CI 1.05–3.98; р < 0,05) and post-discharge mortality (8.7 % vs 6.1 %; RR 1.43; 95 % CI 0.56–3.63; р > 0.05). During the first 6 months after MI we found a tendency of higher mortality rate in females than in males (6.2 % vs 1.8 %; RR 3.41; 95 % CI 0.83–13.9; p > 0.05), but after 6–12 months after discharge males tended to have higher mortality than females (4.3 % vs 2.5 %; RR 0.58; 95 % CI 0.12–2.75; p > 0.05).Conclusion. The most important risk factors for MI in females are diabetes mellitus, arterial hypertension and obesity. MI in women is associated with severe HF development; their immediate prognosis and disease outcome is usually less favorable, than in men.https://klinitsist.abvpress.ru/Klin/article/view/278myocardial infarctioncoronary heart diseaseheart failurerisk factorsarterial hypertensiondiabetes mellitusobesitygender featuresmortalitymyocardial revascularizationcoronary angiographypercutaneous coronary intervention |
| spellingShingle | T. M. Murataliev V. K. Zventsova Yu. N. Neklyudova Z. T. Radzhapova S. Yu. Mukhtarenko THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION Klinicist myocardial infarction coronary heart disease heart failure risk factors arterial hypertension diabetes mellitus obesity gender features mortality myocardial revascularization coronary angiography percutaneous coronary intervention |
| title | THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION |
| title_full | THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION |
| title_fullStr | THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION |
| title_full_unstemmed | THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION |
| title_short | THE ROLE OF GENDER FEATURES IN ACUTE MYOCARDIAL INFARCTION |
| title_sort | role of gender features in acute myocardial infarction |
| topic | myocardial infarction coronary heart disease heart failure risk factors arterial hypertension diabetes mellitus obesity gender features mortality myocardial revascularization coronary angiography percutaneous coronary intervention |
| url | https://klinitsist.abvpress.ru/Klin/article/view/278 |
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