Identification of Candidate Lung Function-Related Plasma Proteins to Pinpoint Drug Targets for Common Pulmonary Diseases: A Comprehensive Multi-Omics Integration Analysis

Identification of Candidate Lung Function-Related Plasma Proteins to Pinpoint Drug Targets for Common Pulmonary Diseases: A Comprehensive Multi-Omics Integration Analysis

The genome-wide association studies (GWAS) of lung disease and lung function indices suffer from challenges to be transformed into clinical interventions, due to a lack of knowledge on the molecular mechanism underlying the GWAS associations. A proteome-wide association study (PWAS) was first perfor...

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Bibliographic Details
Main Authors: Yansong Zhao, Lujia Shen, Ran Yan, Lu Liu, Ping Guo, Shuai Liu, Yingxuan Chen, Zhongshang Yuan, Weiming Gong, Jiadong Ji
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Current Issues in Molecular Biology
Subjects:
proteomics
proteome-wide association study
therapeutic
lung function
bioinformatics methods
Online Access:https://www.mdpi.com/1467-3045/47/3/167
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