Extra medullar Granulocytic sarcoma: a case report of an exceptional localization
Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases. The present study reports the case of a 36-year-old female with a medical history of myelodysplastic syndrome. She was referred because of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Journal of Mind and Medical Sciences |
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| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1230&context=jmms |
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| author | Bouhani Malek Sakhri Saida Jaidane Olfa Adouni Olfa Chargui Riadh Rahal Khaled |
| author_facet | Bouhani Malek Sakhri Saida Jaidane Olfa Adouni Olfa Chargui Riadh Rahal Khaled |
| author_sort | Bouhani Malek |
| collection | DOAJ |
| description | Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases. The present study reports the case of a 36-year-old female with a medical history of myelodysplastic syndrome. She was referred because of a lump in the left breast. We have diagnosed a case of granulocytic sarcoma of the breast by core biopsy. Histology and immunohistochemistry showed hypercellular smears with immature myeloid cells. The blast cells were myeloperoxidase positive.
The patient underwent a lumpectomy. Five months later, she developed a contralateral recurrence, treated by lumpectomy and radiotherapy. Three years later, she developed a recurrence in the left knee.
We report this case for its rarity and as a note of caution to a physician to consider myeloid sarcoma in the differential diagnosis of a breast lump, to provide the correct diagnosis and avoid incorrect treatment of a curable disease. |
| format | Article |
| id | doaj-art-d513aa774e5f4ad08b2915294b4590bb |
| institution | DOAJ |
| issn | 2392-7674 2392-7674 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj-art-d513aa774e5f4ad08b2915294b4590bb2025-08-20T03:19:42ZengMDPI AGJournal of Mind and Medical Sciences2392-76742392-76742020-04-017111011310.22543/7674.71.P110113Extra medullar Granulocytic sarcoma: a case report of an exceptional localizationBouhani Malek0Sakhri Saida1Jaidane Olfa2Adouni Olfa3Chargui Riadh4Rahal Khaled5SALAH AZAIZ INSTITUTE, DEPARTMENT OF ONCOLOGIC SURGERY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIASALAH AZAIZ INSTITUTE, DEPARTMENT OF ONCOLOGIC SURGERY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIASALAH AZAIZ INSTITUTE, DEPARTMENT OF ONCOLOGIC SURGERY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIASALAH AZAIZ INSTITUTE, DEPARTMENT OF ANATOMO-PATHOLOGY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIASALAH AZAIZ INSTITUTE, DEPARTMENT OF ONCOLOGIC SURGERY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIASALAH AZAIZ INSTITUTE, DEPARTMENT OF ONCOLOGIC SURGERY, BOULEVARD 9TH APRIL, TUNIS 1009, TUNISIAGranulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases. The present study reports the case of a 36-year-old female with a medical history of myelodysplastic syndrome. She was referred because of a lump in the left breast. We have diagnosed a case of granulocytic sarcoma of the breast by core biopsy. Histology and immunohistochemistry showed hypercellular smears with immature myeloid cells. The blast cells were myeloperoxidase positive. The patient underwent a lumpectomy. Five months later, she developed a contralateral recurrence, treated by lumpectomy and radiotherapy. Three years later, she developed a recurrence in the left knee. We report this case for its rarity and as a note of caution to a physician to consider myeloid sarcoma in the differential diagnosis of a breast lump, to provide the correct diagnosis and avoid incorrect treatment of a curable disease.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1230&context=jmmsmyeloidsarcomabreastmyelodysplasticsyndrome |
| spellingShingle | Bouhani Malek Sakhri Saida Jaidane Olfa Adouni Olfa Chargui Riadh Rahal Khaled Extra medullar Granulocytic sarcoma: a case report of an exceptional localization Journal of Mind and Medical Sciences myeloid sarcoma breast myelodysplastic syndrome |
| title | Extra medullar Granulocytic sarcoma: a case report of an exceptional localization |
| title_full | Extra medullar Granulocytic sarcoma: a case report of an exceptional localization |
| title_fullStr | Extra medullar Granulocytic sarcoma: a case report of an exceptional localization |
| title_full_unstemmed | Extra medullar Granulocytic sarcoma: a case report of an exceptional localization |
| title_short | Extra medullar Granulocytic sarcoma: a case report of an exceptional localization |
| title_sort | extra medullar granulocytic sarcoma a case report of an exceptional localization |
| topic | myeloid sarcoma breast myelodysplastic syndrome |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1230&context=jmms |
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