Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)

The Himalayan griffon (<i>Gyps himalayensis</i>), an obligate scavenging bird in the Qinghai–Tibet Plateau, provides significant ecological services but is currently listed as near threatened. Despite their importance for conservation, genome-wide screening for microsatellites (or SSRs)...

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Main Authors: Weibin Guo, Dianhua Ke, Changcao Wang, Haiying Fan
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/10/1438
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author Weibin Guo
Dianhua Ke
Changcao Wang
Haiying Fan
author_facet Weibin Guo
Dianhua Ke
Changcao Wang
Haiying Fan
author_sort Weibin Guo
collection DOAJ
description The Himalayan griffon (<i>Gyps himalayensis</i>), an obligate scavenging bird in the Qinghai–Tibet Plateau, provides significant ecological services but is currently listed as near threatened. Despite their importance for conservation, genome-wide screening for microsatellites (or SSRs) in <i>G. himalayensis</i> and the development of corresponding molecular markers have been lacking. This study presents the first in-depth characterization of genome-wide microsatellites in <i>G. himalayensis</i> and the successful development of polymorphic SSR markers. A total of 240,741 microsatellite loci were detected in the <i>G. himalayensis</i> genome, with an average density of 202.2 SSRs per Mb, accounting for 0.44% of the genome. Mononucleotide repeats (53.2%) were the most prevalent among the different microsatellite motif types. Additionally, 100 primer pairs were initially identified, with 17 found to be polymorphic markers. These loci hold significant potential for revealing genotypic diversity in <i>G. himalayensis</i>, thereby laying a foundation for the conservation of this species.
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spelling doaj-art-d513a7140df542b7905060134bf3fac12025-08-20T02:33:39ZengMDPI AGAnimals2076-26152025-05-011510143810.3390/ani15101438Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)Weibin Guo0Dianhua Ke1Changcao Wang2Haiying Fan3School of Life Sciences, Jinggangshan University, Ji’an 343009, ChinaSchool of Life Sciences, Jinggangshan University, Ji’an 343009, ChinaState Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan 430062, ChinaSchool of Life Sciences, Jinggangshan University, Ji’an 343009, ChinaThe Himalayan griffon (<i>Gyps himalayensis</i>), an obligate scavenging bird in the Qinghai–Tibet Plateau, provides significant ecological services but is currently listed as near threatened. Despite their importance for conservation, genome-wide screening for microsatellites (or SSRs) in <i>G. himalayensis</i> and the development of corresponding molecular markers have been lacking. This study presents the first in-depth characterization of genome-wide microsatellites in <i>G. himalayensis</i> and the successful development of polymorphic SSR markers. A total of 240,741 microsatellite loci were detected in the <i>G. himalayensis</i> genome, with an average density of 202.2 SSRs per Mb, accounting for 0.44% of the genome. Mononucleotide repeats (53.2%) were the most prevalent among the different microsatellite motif types. Additionally, 100 primer pairs were initially identified, with 17 found to be polymorphic markers. These loci hold significant potential for revealing genotypic diversity in <i>G. himalayensis</i>, thereby laying a foundation for the conservation of this species.https://www.mdpi.com/2076-2615/15/10/1438avian scavengersvulturesgenomic SSRspolymorphismmolecular marker
spellingShingle Weibin Guo
Dianhua Ke
Changcao Wang
Haiying Fan
Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
Animals
avian scavengers
vultures
genomic SSRs
polymorphism
molecular marker
title Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
title_full Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
title_fullStr Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
title_full_unstemmed Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
title_short Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (<i>Gyps himalayensis</i>)
title_sort genome wide microsatellite characterization and molecular marker development of himalayan griffon i gyps himalayensis i
topic avian scavengers
vultures
genomic SSRs
polymorphism
molecular marker
url https://www.mdpi.com/2076-2615/15/10/1438
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