Evaluation of ototoxic and neurotoxic effects of local diclofenac sodium application

Evaluation of ototoxic and neurotoxic effects of local diclofenac sodium application

Abstract Background We aimed to investigate diclofenac sodium’s ototoxic and neurotoxic effects, which have already been shown to have a cytotoxic effect on cholesteatoma. Material and methods The subjects were divided into three groups: negative control group (S), experimental group (DS group) in w...

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Bibliographic Details
Main Authors: Halil Elden, Ahmet Kara, Ozcan Budak, Sena Genc Elden, Huseyin Cakiroglu, Mehmet Guven, Mahmut Sinan Yilmaz, Deniz Demir
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Diclofenac sodium
Auditory-evoked potentials
Auditory brainstem responses
Facial nerve disorders
Ototoxicity
Online Access:https://doi.org/10.1186/s43163-025-00860-0
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