Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study

<b>Background/Objectives</b>: Time spent in sedentary pursuits is associated with adverse metabolic profiles. Adolescents spend 65–75% of their day in sedentary pursuits; however, evidence among youth is less conclusive. This study examined the effects of an acute 4 h bout of sedentary b...

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Main Authors: Erica G. Soltero, Osamah Salim, Yiming Mirabile, Salma M. Musaad
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Children
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Online Access:https://www.mdpi.com/2227-9067/12/4/513
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author Erica G. Soltero
Osamah Salim
Yiming Mirabile
Salma M. Musaad
author_facet Erica G. Soltero
Osamah Salim
Yiming Mirabile
Salma M. Musaad
author_sort Erica G. Soltero
collection DOAJ
description <b>Background/Objectives</b>: Time spent in sedentary pursuits is associated with adverse metabolic profiles. Adolescents spend 65–75% of their day in sedentary pursuits; however, evidence among youth is less conclusive. This study examined the effects of an acute 4 h bout of sedentary behaviors on cardiometabolic outcomes and energy expenditure in Hispanic adolescents (12–16 years old) with obesity (BMI% ≥ 95th). <b>Methods</b>: This study used a randomized cross-over design to engage participants (N = 12) in two sedentary conditions, an active condition where youth were engaged in two hours of ‘active’ sitting activities (e.g., reading and puzzles) and two hours of passive movie-watching. Whole-room calorimetry was used to assess energy expenditure. Fasting measures of insulin, adiponectin, leptin, and TNF-alpha were collected, followed by post-prandial measures 30 min, 2 h, and 4 h after a standardized meal. Adiposity was assessed using DXA. <b>Results</b>: There was no overall impact of the 4 h sedentary bout on energy expenditure or cardiometabolic risk factors; however, energy expenditure in the active sedentary condition was higher compared to the passive sedentary condition (<i>p</i> = 0.0635, ß estimate = 0.1538). Sex and adiposity did not moderate the relationships among sedentary time, cardiometabolic outcomes, and energy expenditure. <b>Conclusions</b>: Due to power limitations, these results are exploratory; however, they suggest that different types of sedentary behaviors may be more deleterious than others. More studies are needed to understand the context in which sedentary activities occur and the mechanisms by which sedentary pursuits contribute to the development of cardiometabolic disease.
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spelling doaj-art-d508dc1e554546549c73ebe66a0ce1192025-08-20T03:13:48ZengMDPI AGChildren2227-90672025-04-0112451310.3390/children12040513Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover StudyErica G. Soltero0Osamah Salim1Yiming Mirabile2Salma M. Musaad3USDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USAUSDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USAUSDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USAUSDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA<b>Background/Objectives</b>: Time spent in sedentary pursuits is associated with adverse metabolic profiles. Adolescents spend 65–75% of their day in sedentary pursuits; however, evidence among youth is less conclusive. This study examined the effects of an acute 4 h bout of sedentary behaviors on cardiometabolic outcomes and energy expenditure in Hispanic adolescents (12–16 years old) with obesity (BMI% ≥ 95th). <b>Methods</b>: This study used a randomized cross-over design to engage participants (N = 12) in two sedentary conditions, an active condition where youth were engaged in two hours of ‘active’ sitting activities (e.g., reading and puzzles) and two hours of passive movie-watching. Whole-room calorimetry was used to assess energy expenditure. Fasting measures of insulin, adiponectin, leptin, and TNF-alpha were collected, followed by post-prandial measures 30 min, 2 h, and 4 h after a standardized meal. Adiposity was assessed using DXA. <b>Results</b>: There was no overall impact of the 4 h sedentary bout on energy expenditure or cardiometabolic risk factors; however, energy expenditure in the active sedentary condition was higher compared to the passive sedentary condition (<i>p</i> = 0.0635, ß estimate = 0.1538). Sex and adiposity did not moderate the relationships among sedentary time, cardiometabolic outcomes, and energy expenditure. <b>Conclusions</b>: Due to power limitations, these results are exploratory; however, they suggest that different types of sedentary behaviors may be more deleterious than others. More studies are needed to understand the context in which sedentary activities occur and the mechanisms by which sedentary pursuits contribute to the development of cardiometabolic disease.https://www.mdpi.com/2227-9067/12/4/513sedentary behaviorsHispanic healthobesityscreen timecardiometabolic disease
spellingShingle Erica G. Soltero
Osamah Salim
Yiming Mirabile
Salma M. Musaad
Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
Children
sedentary behaviors
Hispanic health
obesity
screen time
cardiometabolic disease
title Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
title_full Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
title_fullStr Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
title_full_unstemmed Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
title_short Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study
title_sort exploring the acute effects of sedentary behaviors on cardiometabolic risk in hispanic adolescents with obesity a randomized crossover study
topic sedentary behaviors
Hispanic health
obesity
screen time
cardiometabolic disease
url https://www.mdpi.com/2227-9067/12/4/513
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