Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism

Bridging to diagnosis is an emerging technique used in end-stage cardiorespiratory failure that prolongs a patient’s life using various modalities of extracorporeal lung support (ECLS) to achieve antemortem diagnosis. Pulmonary tumor embolism occurs when cell clusters travel from primary malignancie...

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Main Authors: Vishnu Vasanthan, Kieran Halloran, Lakshmi Puttagunta, Jayan Nagendran
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2016/3257084
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author Vishnu Vasanthan
Kieran Halloran
Lakshmi Puttagunta
Jayan Nagendran
author_facet Vishnu Vasanthan
Kieran Halloran
Lakshmi Puttagunta
Jayan Nagendran
author_sort Vishnu Vasanthan
collection DOAJ
description Bridging to diagnosis is an emerging technique used in end-stage cardiorespiratory failure that prolongs a patient’s life using various modalities of extracorporeal lung support (ECLS) to achieve antemortem diagnosis. Pulmonary tumor embolism occurs when cell clusters travel from primary malignancies through venous circulation to the lungs, causing respiratory failure through inflammatory and venoocclusive pathways. Due to its nonspecific symptomatology, pulmonary tumor embolism remains an elusive diagnosis antemortem. Herein, we bridge a patient who presented in acute respiratory failure to the diagnosis of pulmonary tumor embolism from a gastric signet-ring cell carcinoma using ECLS modalities including venoarterial extracorporeal membrane oxygenation and centrally cannulated Novalung pumpless extracorporeal lung assist. We demonstrate the utility of this approach in diagnostically uncertain cases in unstable patients who are potentially acceptable ECLS and transplant candidates.
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spelling doaj-art-d50707919cac4e6aa4da250991f1d4f62025-08-20T02:20:00ZengWileyCase Reports in Pulmonology2090-68462090-68542016-01-01201610.1155/2016/32570843257084Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor EmbolismVishnu Vasanthan0Kieran Halloran1Lakshmi Puttagunta2Jayan Nagendran3Department of Surgery, University of Alberta, Edmonton, AB, CanadaDepartment of Medicine, University of Alberta, Edmonton, AB, CanadaDepartment of Medicine, University of Alberta, Edmonton, AB, CanadaDepartment of Surgery, University of Alberta, Edmonton, AB, CanadaBridging to diagnosis is an emerging technique used in end-stage cardiorespiratory failure that prolongs a patient’s life using various modalities of extracorporeal lung support (ECLS) to achieve antemortem diagnosis. Pulmonary tumor embolism occurs when cell clusters travel from primary malignancies through venous circulation to the lungs, causing respiratory failure through inflammatory and venoocclusive pathways. Due to its nonspecific symptomatology, pulmonary tumor embolism remains an elusive diagnosis antemortem. Herein, we bridge a patient who presented in acute respiratory failure to the diagnosis of pulmonary tumor embolism from a gastric signet-ring cell carcinoma using ECLS modalities including venoarterial extracorporeal membrane oxygenation and centrally cannulated Novalung pumpless extracorporeal lung assist. We demonstrate the utility of this approach in diagnostically uncertain cases in unstable patients who are potentially acceptable ECLS and transplant candidates.http://dx.doi.org/10.1155/2016/3257084
spellingShingle Vishnu Vasanthan
Kieran Halloran
Lakshmi Puttagunta
Jayan Nagendran
Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
Case Reports in Pulmonology
title Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
title_full Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
title_fullStr Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
title_full_unstemmed Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
title_short Extracorporeal Lung Support as a Bridge to Diagnosis of Pulmonary Tumor Embolism
title_sort extracorporeal lung support as a bridge to diagnosis of pulmonary tumor embolism
url http://dx.doi.org/10.1155/2016/3257084
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