Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report
Abstract Background Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare. We experienced a case of synchronous gastric cancer and lung cancer who was treated by nivolumab and laparoscopic gastrectomy. Case presentation A 63-year-old male consulted our institution...
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| Format: | Article |
| Language: | English |
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Japan Surgical Society
2020-10-01
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| Series: | Surgical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s40792-020-01053-y |
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| author | Shunji Endo Yoshinori Fujiwara Koji Kurose Masaharu Higashida Hisako Kubota Yuko Okamoto Shumei Mineta Hironori Tanaka Toshimasa Okada Atsushi Tsuruta Takashi Akiyama Toru Oga Tomio Ueno |
| author_facet | Shunji Endo Yoshinori Fujiwara Koji Kurose Masaharu Higashida Hisako Kubota Yuko Okamoto Shumei Mineta Hironori Tanaka Toshimasa Okada Atsushi Tsuruta Takashi Akiyama Toru Oga Tomio Ueno |
| author_sort | Shunji Endo |
| collection | DOAJ |
| description | Abstract Background Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare. We experienced a case of synchronous gastric cancer and lung cancer who was treated by nivolumab and laparoscopic gastrectomy. Case presentation A 63-year-old male consulted our institution and was found to have gastric cancer cT1(SM)N0M0 Stage IA and lung cancer cT2N2M1(PUL) Stage IV. He received eight chemotherapy treatments plus radiation, but the lung disease remained progressive. Finally, he received nivolumab therapy and complete response of both cancers was obtained. The gastric cancer recurred, but was successfully treated by laparoscopic gastrectomy. The resected specimen revealed three lesions, each being pT1aN0M0 Stage IA. The primary gastric cancer seemed to have completely vanished without scarring. Conclusions This was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab. |
| format | Article |
| id | doaj-art-d4ff439622d44f05b66d62a84cc3550f |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2020-10-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-d4ff439622d44f05b66d62a84cc3550f2025-08-20T03:39:26ZengJapan Surgical SocietySurgical Case Reports2198-77932020-10-01611610.1186/s40792-020-01053-ySuccessful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case reportShunji Endo0Yoshinori Fujiwara1Koji Kurose2Masaharu Higashida3Hisako Kubota4Yuko Okamoto5Shumei Mineta6Hironori Tanaka7Toshimasa Okada8Atsushi Tsuruta9Takashi Akiyama10Toru Oga11Tomio Ueno12Department of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Respiratory Medicine, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolDepartment of Pathology, Kawasaki Medical SchoolDepartment of Respiratory Medicine, Kawasaki Medical SchoolDepartment of Digestive Surgery, Kawasaki Medical SchoolAbstract Background Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare. We experienced a case of synchronous gastric cancer and lung cancer who was treated by nivolumab and laparoscopic gastrectomy. Case presentation A 63-year-old male consulted our institution and was found to have gastric cancer cT1(SM)N0M0 Stage IA and lung cancer cT2N2M1(PUL) Stage IV. He received eight chemotherapy treatments plus radiation, but the lung disease remained progressive. Finally, he received nivolumab therapy and complete response of both cancers was obtained. The gastric cancer recurred, but was successfully treated by laparoscopic gastrectomy. The resected specimen revealed three lesions, each being pT1aN0M0 Stage IA. The primary gastric cancer seemed to have completely vanished without scarring. Conclusions This was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab.http://link.springer.com/article/10.1186/s40792-020-01053-yStomach neoplasmsLung neoplasmsLaparoscopic gastrectomyNivolumab |
| spellingShingle | Shunji Endo Yoshinori Fujiwara Koji Kurose Masaharu Higashida Hisako Kubota Yuko Okamoto Shumei Mineta Hironori Tanaka Toshimasa Okada Atsushi Tsuruta Takashi Akiyama Toru Oga Tomio Ueno Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report Surgical Case Reports Stomach neoplasms Lung neoplasms Laparoscopic gastrectomy Nivolumab |
| title | Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report |
| title_full | Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report |
| title_fullStr | Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report |
| title_full_unstemmed | Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report |
| title_short | Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report |
| title_sort | successful treatment of gastric cancer after complete response of lung cancer by nivolumab a case report |
| topic | Stomach neoplasms Lung neoplasms Laparoscopic gastrectomy Nivolumab |
| url | http://link.springer.com/article/10.1186/s40792-020-01053-y |
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