Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy

Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy

Abstract Purposes Previous studies have demonstrated that proliferation, stroma or immunity strongly influence the prognosis and therapeutic resistance of diffuse large B-cell lymphoma (DLBCL). Herein, we aimed to integrate proliferation, stromal, and immune (PSI) features to systematically evaluate...

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Bibliographic Details
Main Authors: Xiaojie Liang, Jia Guo, Baiwei Luo, Weixiang Lu, Qiumin Chen, Yeling Deng, Yunong Yang, Liang Wang
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Journal of Big Data
Subjects:
DLBCL
Proliferation
Stromal
Immune
Risk stratification
SRM
Online Access:https://doi.org/10.1186/s40537-025-01067-z
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