Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review

Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America. Paromomycin, an aminoglycoside drug, is frequently used for the treatment of visceral leishm...

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Main Authors: Pashupati Pokharel, Rakesh Ghimire, Pratik Lamichhane
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2021/8629039
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author Pashupati Pokharel
Rakesh Ghimire
Pratik Lamichhane
author_facet Pashupati Pokharel
Rakesh Ghimire
Pratik Lamichhane
author_sort Pashupati Pokharel
collection DOAJ
description Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America. Paromomycin, an aminoglycoside drug, is frequently used for the treatment of visceral leishmaniasis. Despite limited therapies for visceral leishmaniasis and emerging drug resistance, a proper review on the action of paromomycin for kala-azar is lacking. This systematic review aims to look for the efficacy and safety aspects of paromomycin for the treatment of visceral leishmaniasis.
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institution Kabale University
issn 1687-9686
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publishDate 2021-01-01
publisher Wiley
record_format Article
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spelling doaj-art-d4f79bf12b2f4ee9ada3b94a53c4cecb2025-02-03T07:23:56ZengWileyJournal of Tropical Medicine1687-96861687-96942021-01-01202110.1155/2021/86290398629039Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic ReviewPashupati Pokharel0Rakesh Ghimire1Pratik Lamichhane2Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, NepalDepartment of Clinical Pharmacology, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, NepalMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, NepalVisceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America. Paromomycin, an aminoglycoside drug, is frequently used for the treatment of visceral leishmaniasis. Despite limited therapies for visceral leishmaniasis and emerging drug resistance, a proper review on the action of paromomycin for kala-azar is lacking. This systematic review aims to look for the efficacy and safety aspects of paromomycin for the treatment of visceral leishmaniasis.http://dx.doi.org/10.1155/2021/8629039
spellingShingle Pashupati Pokharel
Rakesh Ghimire
Pratik Lamichhane
Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
Journal of Tropical Medicine
title Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
title_full Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
title_fullStr Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
title_full_unstemmed Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
title_short Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
title_sort efficacy and safety of paromomycin for visceral leishmaniasis a systematic review
url http://dx.doi.org/10.1155/2021/8629039
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AT rakeshghimire efficacyandsafetyofparomomycinforvisceralleishmaniasisasystematicreview
AT pratiklamichhane efficacyandsafetyofparomomycinforvisceralleishmaniasisasystematicreview