The lysosomotropic drug LeuLeu-OMe induces lysosome disruption and autophagy-independent cell death in Trypanosoma brucei
Background: Trypanosoma brucei is a blood-borne, protozoan parasite that causes African sleeping sickness in humans and nagana in animals. The current chemotherapy relies on only a handful of drugs that display undesirable toxicity, poor efficacy and drug-resistance. In this study, we explored t...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2015-07-01
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| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/the-lysosomotropic-drug-leuleu-ome-induces-lysosome-disruption-and-autophagy-independent-cell-death-in-trypanosoma-brucei/ |
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