The response to anti-seizure medications and the development of pharmacoresistant epilepsy in malformations of cortical development

The response to anti-seizure medications and the development of pharmacoresistant epilepsy in malformations of cortical development

Abstract Background Malformations of cortical development (MCD) are a group of congenital brain malformation disorders commonly associated with pharmacoresistant epilepsy (PRE). While studies often focus on surgery outcomes, the pharmacological treatment is still imperative and the odyssey to PRE re...

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Main Authors: Pu Miao, Meiping Ying, Ruotong Chen, Yuyu Yang, Yao Ding, Junming Zhu, Jianhua Feng, Jin Wang, Thandar Aung, Shuang Wang, Bo Jin
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medicine
Subjects:
Malformations of cortical development
Pharmacoresistant epilepsy
Sodium channel blockers
Online Access:https://doi.org/10.1186/s12916-025-04019-9
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