A comprehensive overview of ovarian cancer stem cells: correlation with high recurrence rate, underlying mechanisms, and therapeutic opportunities
Abstract Ovarian cancer is one of the most lethal gynecological malignancies, with a recurrence rate of 70–80%, particularly in patients diagnosed at advanced stages (stage III or IV), where the five-year survival rate falls below 30%. A key driver of this recurrence is the presence of cancer stem c...
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| Main Authors: | Hadi Alizadeh, Parastoo Akbarabadi, Alireza Dadfar, Mohammad Reza Tareh, Bahram Soltani |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Molecular Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12943-025-02345-3 |
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