Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report

Both primary rectal lymphoma (PRL) and primary hepatic lymphoma are rare entities, concomitant NHL in rectum and liver is an extremely rare coincidence. Cases of primary colonic lymphoma however can be found in literature. We report an extremely rare case of PRL with synchronous liver involvement af...

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Main Authors: Kartick Rastogi, Sandeep Jain, Shantanu Sharma, Arpita Jindal
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-01-01
Series:Indian Journal of Medical and Paediatric Oncology
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Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=93;epage=95;aulast=Rastogi
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author Kartick Rastogi
Sandeep Jain
Shantanu Sharma
Arpita Jindal
author_facet Kartick Rastogi
Sandeep Jain
Shantanu Sharma
Arpita Jindal
author_sort Kartick Rastogi
collection DOAJ
description Both primary rectal lymphoma (PRL) and primary hepatic lymphoma are rare entities, concomitant NHL in rectum and liver is an extremely rare coincidence. Cases of primary colonic lymphoma however can be found in literature. We report an extremely rare case of PRL with synchronous liver involvement after obtaining written informed consent, with a review of available literature. The case was provisionally diagnosed to be an adenocarcinoma of rectum with liver metastasis, with final confirmation on immunohistochemistry. PRL with synchronous liver involvement is an extremely rare coincidence. It is usually confused with more common adenocarcinoma of rectum with liver metastasis posing diagnostic challenges. The optimal management of PRL has never been validated through randomized trials. The treatment options include chemotherapy, radiation, surgical treatment, or a combination of these. Chemotherapeutic agents of choice are the cyclophosphamide, doxorubicin, vincristine, and prednisone regimen, with or without monoclonal antibody rituximab.
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publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-d4ecad3dcd244e8290aa0b713e6e24ad2025-08-20T03:24:39ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292020-01-01411939510.4103/ijmpo.ijmpo_103_18Primary rectal lymphoma with synchronous liver involvement: An extremely rare case reportKartick RastogiSandeep JainShantanu SharmaArpita JindalBoth primary rectal lymphoma (PRL) and primary hepatic lymphoma are rare entities, concomitant NHL in rectum and liver is an extremely rare coincidence. Cases of primary colonic lymphoma however can be found in literature. We report an extremely rare case of PRL with synchronous liver involvement after obtaining written informed consent, with a review of available literature. The case was provisionally diagnosed to be an adenocarcinoma of rectum with liver metastasis, with final confirmation on immunohistochemistry. PRL with synchronous liver involvement is an extremely rare coincidence. It is usually confused with more common adenocarcinoma of rectum with liver metastasis posing diagnostic challenges. The optimal management of PRL has never been validated through randomized trials. The treatment options include chemotherapy, radiation, surgical treatment, or a combination of these. Chemotherapeutic agents of choice are the cyclophosphamide, doxorubicin, vincristine, and prednisone regimen, with or without monoclonal antibody rituximab.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=93;epage=95;aulast=Rastoginon-hodgkin's lymphomaprimary hepatic lymphomaprimary rectal lymphoma
spellingShingle Kartick Rastogi
Sandeep Jain
Shantanu Sharma
Arpita Jindal
Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
Indian Journal of Medical and Paediatric Oncology
non-hodgkin's lymphoma
primary hepatic lymphoma
primary rectal lymphoma
title Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
title_full Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
title_fullStr Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
title_full_unstemmed Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
title_short Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
title_sort primary rectal lymphoma with synchronous liver involvement an extremely rare case report
topic non-hodgkin's lymphoma
primary hepatic lymphoma
primary rectal lymphoma
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=93;epage=95;aulast=Rastogi
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AT sandeepjain primaryrectallymphomawithsynchronousliverinvolvementanextremelyrarecasereport
AT shantanusharma primaryrectallymphomawithsynchronousliverinvolvementanextremelyrarecasereport
AT arpitajindal primaryrectallymphomawithsynchronousliverinvolvementanextremelyrarecasereport