Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection
A 90-year-old African American female with multiple comorbidities and a severe COVID-19 infection was discharged home in stable condition after two weeks of hospitalization. A week later, she developed new-onset generalized tonic-clonic seizures requiring readmission to the hospital. The patient’s c...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/5564802 |
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| author | Ketino Kobaidze Yoo Mee Shin Mariam Japaridze Ioannis Karakis Xin Wu |
| author_facet | Ketino Kobaidze Yoo Mee Shin Mariam Japaridze Ioannis Karakis Xin Wu |
| author_sort | Ketino Kobaidze |
| collection | DOAJ |
| description | A 90-year-old African American female with multiple comorbidities and a severe COVID-19 infection was discharged home in stable condition after two weeks of hospitalization. A week later, she developed new-onset generalized tonic-clonic seizures requiring readmission to the hospital. The patient’s clinical course and brain imaging supported PRES. Her mentation returned to baseline with supportive care and anticonvulsant treatment. Follow-up brain MRI four months later demonstrated resolution of FLAIR signal abnormalities confirming PRES. SARS-CoV-2 insult on the cerebrovascular endothelial cells likely continued and despite the clinical recovery eventually resulted in PRES. We believe that this is the first case describing the presentation of PRES after recovery from severe acute COVID-19 infection. |
| format | Article |
| id | doaj-art-d4e8d71999a340979abb6f99afe3d403 |
| institution | OA Journals |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-d4e8d71999a340979abb6f99afe3d4032025-08-20T02:20:00ZengWileyCase Reports in Neurological Medicine2090-66682090-66762021-01-01202110.1155/2021/55648025564802Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 InfectionKetino Kobaidze0Yoo Mee Shin1Mariam Japaridze2Ioannis Karakis3Xin Wu4Associate Professor of Medicine, Emory University School of Medicine, Division of Hospital Medicine 550 Peachtree Street, Atlanta, GA 30308, USADivision of Hospital Medicine, Emory University School of Medicine, Atlanta, GA 30308, USARoss University School of Medicine, New Jersey, USADepartment of Neurology, Emory University School of Medicine, Atlanta, GA 30308, USADepartment of Radiology and Imaging Science, Emory University School of Medicine, Atlanta, GA 30308, USAA 90-year-old African American female with multiple comorbidities and a severe COVID-19 infection was discharged home in stable condition after two weeks of hospitalization. A week later, she developed new-onset generalized tonic-clonic seizures requiring readmission to the hospital. The patient’s clinical course and brain imaging supported PRES. Her mentation returned to baseline with supportive care and anticonvulsant treatment. Follow-up brain MRI four months later demonstrated resolution of FLAIR signal abnormalities confirming PRES. SARS-CoV-2 insult on the cerebrovascular endothelial cells likely continued and despite the clinical recovery eventually resulted in PRES. We believe that this is the first case describing the presentation of PRES after recovery from severe acute COVID-19 infection.http://dx.doi.org/10.1155/2021/5564802 |
| spellingShingle | Ketino Kobaidze Yoo Mee Shin Mariam Japaridze Ioannis Karakis Xin Wu Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection Case Reports in Neurological Medicine |
| title | Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection |
| title_full | Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection |
| title_fullStr | Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection |
| title_full_unstemmed | Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection |
| title_short | Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection |
| title_sort | posterior reversible leukoencephalopathy syndrome in a patient after acute covid 19 infection |
| url | http://dx.doi.org/10.1155/2021/5564802 |
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