Peri-adolescent bupropion treatment alters adult operant responding and is associated with reduced ΔFosB and thin spine density in the nucleus accumbens in rats
Exposure to pharmacological agents can disrupt brain development, producing maladaptive neurobehavioural output. The reward system is established over a protracted developmental time period which allows for age-specific vulnerabilities to external influence. Bupropion (BUP) inhibits dopamine (DA) an...
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| Main Authors: | Shannon N. Smith, Matthew R. Holahan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Brain Research Bulletin |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923025002540 |
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