Distribution of FoxP3+regulatoryT-cells in rat’spancreatic lymph nodes under streptozotocin-induced diabetes and metformin administration

Distribution of FoxP3+regulatoryT-cells in rat’spancreatic lymph nodes under streptozotocin-induced diabetes and metformin administration

Type 1 diabetes mellitus is a T-cellmediated autoimmune disease characterized by the destruction of β-cells of the pancreas. Numerous studies have demonstrated the key role of FoxP3+ regulatory T-cells in the development of type 1 diabetes. The aim of our study:1) to determine the expression patt...

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Bibliographic Details
Main Authors: D. A. Putilin, A. M. Kamyshnyi
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2015-04-01
Series:Patologìâ
Subjects:
Diabetes mellitus
FoxP3
Metformin
Treg
Online Access:http://pat.zsmu.edu.ua/article/view/42830/39227
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