Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this
Background The management of pulmonary nodules plays a critical role in early detection of lung cancer. Computed tomography (CT) has led to a stage-shift towards early-stage lung cancer, but regional differences in survival rates have been reported in Denmark. This study aimed to evaluate whether va...
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Taylor & Francis Group
2024-12-01
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| Series: | European Clinical Respiratory Journal |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20018525.2024.2313311 |
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| author | M. Borg U. Bodtger K. Kristensen G. Alstrup T. Mamaeva A. Arshad CB. Laursen O. Hilberg M. Brun Andersen T Riis Rasmussen |
| author_facet | M. Borg U. Bodtger K. Kristensen G. Alstrup T. Mamaeva A. Arshad CB. Laursen O. Hilberg M. Brun Andersen T Riis Rasmussen |
| author_sort | M. Borg |
| collection | DOAJ |
| description | Background The management of pulmonary nodules plays a critical role in early detection of lung cancer. Computed tomography (CT) has led to a stage-shift towards early-stage lung cancer, but regional differences in survival rates have been reported in Denmark. This study aimed to evaluate whether variations in nodule management among Danish health regions contributed to these differences.Material and Methods The Danish Health Data Authority and Danish Lung Cancer Registry provided data on CT usage and lung cancer stage distribution, respectively. Auditing of lung cancer stage IA patient referrals and nodule management of stage IV lung cancer patients was conducted in seven Danish lung cancer investigation centers, covering four of the five Danish health regions. CT scans were performed up to 2 years before the patients’ diagnosis from 2019 to 2021.Results CT usage has increased steadily in Denmark over the past decade, with a simultaneous increase in the proportion of early-stage lung cancers, particularly stage IA. However, one Danish health region, Region Zealand, exhibited lower rates of early-stage lung cancer and overall survival despite a CT usage roughly similar to that of the other health regions. The audit did not find significant differences in pulmonary nodule management or a higher number of missed nodules by radiologists in this region compared to others.Conclusion This study suggests that a high CT scan volume alone is not sufficient for the early detection of lung cancer. Factors beyond hospital management practices, such as patient-related delays in socioeconomically disadvantaged areas, may contribute to regional differences in survival rates. This has implications for future strategies for reducing these differences. |
| format | Article |
| id | doaj-art-d4c55656850943fea41524988eee5592 |
| institution | OA Journals |
| issn | 2001-8525 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj-art-d4c55656850943fea41524988eee55922025-08-20T02:07:23ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252024-12-0111110.1080/20018525.2024.2313311Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve thisM. Borg0U. Bodtger1K. Kristensen2G. Alstrup3T. Mamaeva4A. Arshad5CB. Laursen6O. Hilberg7M. Brun Andersen8T Riis Rasmussen9Department of Internal Medicine, Lillebaelt Hospital Vejle, Vejle, DenmarkRespiratory Research Unit PLUZ, Department of Respiratory Medicine, Zealand University Hospital Næstved & Roskilde, Næstved, DenmarkDepartment of Internal Medicine, Gødstrup Hospital, Herning, DenmarkRespiratory Research Unit PLUZ, Department of Respiratory Medicine, Zealand University Hospital Næstved & Roskilde, Næstved, DenmarkDepartment of Respiratory Medicine, Odense University Hospital, Odense, DenmarkDepartment of Respiratory Medicine, Odense University Hospital, Odense, DenmarkDepartment of Respiratory Medicine, Odense University Hospital, Odense, DenmarkDepartment of Internal Medicine, Lillebaelt Hospital Vejle, Vejle, DenmarkDepartment of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, DenmarkDepartment of Respiratory Medicine and Allergy, Aarhus University Hospital, Aarhus, DenmarkBackground The management of pulmonary nodules plays a critical role in early detection of lung cancer. Computed tomography (CT) has led to a stage-shift towards early-stage lung cancer, but regional differences in survival rates have been reported in Denmark. This study aimed to evaluate whether variations in nodule management among Danish health regions contributed to these differences.Material and Methods The Danish Health Data Authority and Danish Lung Cancer Registry provided data on CT usage and lung cancer stage distribution, respectively. Auditing of lung cancer stage IA patient referrals and nodule management of stage IV lung cancer patients was conducted in seven Danish lung cancer investigation centers, covering four of the five Danish health regions. CT scans were performed up to 2 years before the patients’ diagnosis from 2019 to 2021.Results CT usage has increased steadily in Denmark over the past decade, with a simultaneous increase in the proportion of early-stage lung cancers, particularly stage IA. However, one Danish health region, Region Zealand, exhibited lower rates of early-stage lung cancer and overall survival despite a CT usage roughly similar to that of the other health regions. The audit did not find significant differences in pulmonary nodule management or a higher number of missed nodules by radiologists in this region compared to others.Conclusion This study suggests that a high CT scan volume alone is not sufficient for the early detection of lung cancer. Factors beyond hospital management practices, such as patient-related delays in socioeconomically disadvantaged areas, may contribute to regional differences in survival rates. This has implications for future strategies for reducing these differences.https://www.tandfonline.com/doi/10.1080/20018525.2024.2313311Lung cancerpulmonary nodulescomputed tomographysurvivalearly-stage lung cancer |
| spellingShingle | M. Borg U. Bodtger K. Kristensen G. Alstrup T. Mamaeva A. Arshad CB. Laursen O. Hilberg M. Brun Andersen T Riis Rasmussen Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this European Clinical Respiratory Journal Lung cancer pulmonary nodules computed tomography survival early-stage lung cancer |
| title | Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this |
| title_full | Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this |
| title_fullStr | Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this |
| title_full_unstemmed | Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this |
| title_short | Incidental pulmonary nodules may lead to a high proportion of early-stage lung cancer: but it requires more than a high CT volume to achieve this |
| title_sort | incidental pulmonary nodules may lead to a high proportion of early stage lung cancer but it requires more than a high ct volume to achieve this |
| topic | Lung cancer pulmonary nodules computed tomography survival early-stage lung cancer |
| url | https://www.tandfonline.com/doi/10.1080/20018525.2024.2313311 |
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