Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report
Neuroleptic malignant syndrome (NMS) is a rare but fatal condition, with a high mortality rate. NMS is characterized by altered mental status, fever, myoclonus, autonomic dysfunctions, and elevated creatinine phosphokinase. The clinical manifestations may be confused with alcohol-related symptoms, t...
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| Format: | Article |
| Language: | English |
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Korean Society of Traumatology
2023-09-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://jtraumainj.org/upload/pdf/jti-2022-0048.pdf |
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| author | Byungchul Yu Ji Yeon Lee Yong Beom Kim Hee Yeon Park Junsu Jung Youn Yi Jo |
| author_facet | Byungchul Yu Ji Yeon Lee Yong Beom Kim Hee Yeon Park Junsu Jung Youn Yi Jo |
| author_sort | Byungchul Yu |
| collection | DOAJ |
| description | Neuroleptic malignant syndrome (NMS) is a rare but fatal condition, with a high mortality rate. NMS is characterized by altered mental status, fever, myoclonus, autonomic dysfunctions, and elevated creatinine phosphokinase. The clinical manifestations may be confused with alcohol-related symptoms, trauma, sepsis, postoperative agitation, or malignant hyperthermia. A 69-year-old male patient with alcohol withdrawal was admitted to the operating theatre to rule out septic shock due to mesenteric injury after multiple trauma. He was suspected NMS with abrupt increase body temperature to 41.7°C after haloperidol administration. Active cooling and rapid fluid infusion was done during anesthesia. Delayed diagnosis and treatment of NMS lead to catastrophic result. Therefore, if the patient's past medical history is unknown or clinical symptoms develop that are suggestive of NMS, early treatment must be considered. |
| format | Article |
| id | doaj-art-d4afb573dfed46608cb3e7c52be258c9 |
| institution | Kabale University |
| issn | 2799-4317 2287-1683 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-d4afb573dfed46608cb3e7c52be258c92025-01-16T05:40:00ZengKorean Society of TraumatologyJournal of Trauma and Injury2799-43172287-16832023-09-0136324925210.20408/jti.2022.00481235Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case reportByungchul Yu0Ji Yeon Lee1Yong Beom Kim2Hee Yeon Park3Junsu Jung4Youn Yi Jo5 Department of Trauma Surgery, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, KoreaNeuroleptic malignant syndrome (NMS) is a rare but fatal condition, with a high mortality rate. NMS is characterized by altered mental status, fever, myoclonus, autonomic dysfunctions, and elevated creatinine phosphokinase. The clinical manifestations may be confused with alcohol-related symptoms, trauma, sepsis, postoperative agitation, or malignant hyperthermia. A 69-year-old male patient with alcohol withdrawal was admitted to the operating theatre to rule out septic shock due to mesenteric injury after multiple trauma. He was suspected NMS with abrupt increase body temperature to 41.7°C after haloperidol administration. Active cooling and rapid fluid infusion was done during anesthesia. Delayed diagnosis and treatment of NMS lead to catastrophic result. Therefore, if the patient's past medical history is unknown or clinical symptoms develop that are suggestive of NMS, early treatment must be considered.http://jtraumainj.org/upload/pdf/jti-2022-0048.pdfalcohol withdrawal deliriumneuroleptic malignant syndromewounds and injuriescase reports |
| spellingShingle | Byungchul Yu Ji Yeon Lee Yong Beom Kim Hee Yeon Park Junsu Jung Youn Yi Jo Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report Journal of Trauma and Injury alcohol withdrawal delirium neuroleptic malignant syndrome wounds and injuries case reports |
| title | Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report |
| title_full | Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report |
| title_fullStr | Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report |
| title_full_unstemmed | Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report |
| title_short | Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report |
| title_sort | management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in korea a case report |
| topic | alcohol withdrawal delirium neuroleptic malignant syndrome wounds and injuries case reports |
| url | http://jtraumainj.org/upload/pdf/jti-2022-0048.pdf |
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