Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics

Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics

Objective·To explore the heterogeneity in single-cell genomics between human-induced pluripotent stem cell (iPSC)-derived macrophages (IPSDM) and human peripheral blood-derived macrophages (PBDM).Methods·iPSCs were differentiated into IPSDMs in vitro using a feeder-free and serum-free protocol. The...

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Bibliographic Details
Main Authors: ZHANG Yutong, HOU Guojun, SHEN Nan
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2024-12-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
induced pluripotent stem cell (ipsc)
cell differentiation
macrophage
single-cell gene expression analysis
Online Access:https://xuebao.shsmu.edu.cn/article/2024/1674-8115/1674-8115-2024-44-12-1477.shtml
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