Are Salivary and Plasma Levels of Toll-Like Receptors 2 and 4 Elevated in Subjects With Chronic Periodontitis?: A Systematic Review and Meta-Analysis

Are Salivary and Plasma Levels of Toll-Like Receptors 2 and 4 Elevated in Subjects With Chronic Periodontitis?: A Systematic Review and Meta-Analysis

Toll-like receptors (TLR2 and TLR4) are crucial in the detection of pathogen-associated molecular patterns (PAMPs) during periodontitis, resulting in exacerbated production of proinflammatory cytokines and ultimately tissue damage and bone loss associated with this periodontal disease. This systemat...

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Bibliographic Details
Main Authors: Mario Alberto Alarcón-Sánchez, Ruth Rodríguez-Montaño, Sarah Monserrat Lomelí-Martínez, Cristina Hermila Martínez-Bugarin, Seyed Ali Mosaddad, Artak Heboyan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/ijin/7405066
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