Spatial metabolomics in mental disorders and traditional Chinese medicine: a review

Spatial metabolomics in mental disorders and traditional Chinese medicine: a review

Spatial metabolomics is an emerging technology that integrates mass spectrometry imaging (MSI) with metabolomics, offering a novel visual perspective for traditional metabolomics analysis. This technology enables in-depth analysis in three dimensions: qualitative, quantitative, and localization of m...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chaofang Lei, Jiaxu Chen, Zhigang Chen, Chongyang Ma, Xudong Chen, Xiongxing Sun, Xukun Tang, Jun Deng, Shiliang Wang, Junlin Jiang, Dahua Wu, Le Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	mental disorders traditional Chinese medicine spatial metabolomics mass spectrometry imaging DESI-MSI MALDI-MSI
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1449639/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Integrated morphological observation, metabolomics, and transcriptomics to investigate the effect of growth years on the quality of Atractylodes macrocephala Koidz
by: Xiaoxuan Cui, et al.
Published: (2025-07-01)

Illustrate the metabolic regulatory effects of Ganoderma Lucidum polysaccharides on cognitive dysfunction in formaldehyde-exposed mouse brain by mass spectrometry imaging
by: Wen Wang, et al.
Published: (2025-04-01)

A Metabolomics Exploration of Young Lotus Seeds Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
by: Ying Chen, et al.
Published: (2025-08-01)

The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses
by: Dustyn Barnette, et al.
Published: (2024-12-01)

Delineating lipidomic landscapes in human and mouse ovaries: Spatial signatures and chemically-induced alterations via MALDI mass spectrometry imaging
by: Natalia Pascuali, et al.
Published: (2024-12-01)

Microscopy and spatial-metabolomics identify tissue-specific metabolic pathways uncovering salinity and drought tolerance mechanisms in Avicennia marina and Phoenix dactylifera roots
by: Paula Oyarce, et al.
Published: (2025-01-01)

Unveiling the processing mechanism of Hezi-decoction-processed Tiebangchui: a synthesis approach using UPLC-Q-TOF-MS-based metabolomics and DESI-MSI
by: Zhen Zhou, et al.
Published: (2025-04-01)

Certain pMMR colorectal cancer patients should undergo additional MSI-PCR testing to reduce the risk of misdiagnosing MSI-H and Lynch syndrome
by: Jinglin Huang, et al.
Published: (2025-07-01)

V-STAR: A Cloud-Based Tool for Satellite Detection and Mapping of Volcanic Thermal Anomalies
by: Simona Cariello, et al.
Published: (2025-05-01)

Influence of Sulfur Fumigation on Angelicae Dahuricae Radix: Insights from Chemical Profiles, MALDI-MSI and Anti-Inflammatory Activities
by: Changshun Wang, et al.
Published: (2024-12-01)

Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences
by: Shih‐Ching Chang, et al.
Published: (2020-01-01)

Tislelizumab-induced hemophagocytic lymphohistiocytosis in a patient with microsatellite instability-high colon cancer and coexisting systemic lupus erythematosus: a case report and literature review
by: Pengqing Jiao, et al.
Published: (2025-08-01)

Substitution of silver-thiosulfate (STS) with some essential oils on vase- life of cut carnation Cv. Liberty
by: A. Ebrahimzadeh, et al.
Published: (2017-03-01)

Tendomodulin in pan-cancer analysis: exploring its impact on immune modulation and uncovering functional insights in colorectal cancer
by: Jingfeng Chen, et al.
Published: (2025-02-01)

Stock Assessment of Marine Elasmobranchs (Sharks and Rays) in the Bay of Bengal, Bangladesh
by: Dwipika Gope, et al.
Published: (2025-06-01)

High-resolution 3D spatial distribution of complex microbial colonies revealed by mass spectrometry imaging
by: Yuting Shen, et al.
Published: (2025-07-01)

Computed tomography radiomics to predict microsatellite instability status and immunotherapy response in gastric cancer
by: Zhou Li, et al.
Published: (2025-08-01)

Microsatellite instability and mismatch repair deficiency in bladder urothelial carcinoma: a Tunisian single-center study
by: Ahlem Bdioui, et al.
Published: (2025-05-01)

Application of metabolomics in quality control of traditional Chinese medicines: a review
by: Peiran Ji, et al.
Published: (2024-11-01)

Fraction of Genome Altered, Age, Microsatellite Instability Score, Tumor Mutational Burden, Cancer Type, Metastasis Status, and Choice of Cancer Therapy Predict Overall Survival in Multiple Machine Learning Models
by: Guillaume Mestrallet
Published: (2025-02-01)

Localized Rectal Cancer: Indian Consensus and Guidelines
by: Viraj Lavingia, et al.
Published: (2024-12-01)

Case Report: A case of synchronous multiple early gastric cancer with a microsatellite instability-high phenotype
by: Xinshuo Wang, et al.
Published: (2025-04-01)

Metabolism and spatial transcription resolved heterogeneity of glutamine metabolism in cervical carcinoma
by: Qian Liu, et al.
Published: (2024-12-01)

Mass spectrometry-based metabolomic as a powerful tool to unravel the component and mechanism in TCM
by: Guang-Qin Liao, et al.
Published: (2025-05-01)

A Genetic Make Up of Italian Lipizzan Horse Through Uniparental Markers to Preserve Historical Pedigrees
by: Alessandra Crisà, et al.
Published: (2024-12-01)

Pathologic complete response after Sintilimab combined with FOLFOX therapy in MSI-H type patients with locally advanced GC: a case report
by: Xiaoke Wang, et al.
Published: (2025-05-01)

Inter-Sensor Level 1 Radiometric Comparisons Using Deep Convective Clouds
by: Louis Rivoire, et al.
Published: (2024-11-01)

Whole-body mass spectrometry imaging reveals the systemic metabolic disorder and catecholamines biosynthesis alteration on heart-gut axis in heart failure rat
by: Zhengyu Fang, et al.
Published: (2025-07-01)

Immunohistochemical‐Based Molecular Typing of ACRG Combined With Immune‐Associated PD‐L1 Expression Can Predict the Prognosis of Gastric Cancer
by: Fang Li, et al.
Published: (2025-04-01)

METODOLOGICAL ISSUES IN PROTEIN AND LIPIDIC EXPRESSIONS IN BRAIN TISSUE EXPOSED TO Co60 BASED ON DESI/MALDI-MSI
by: Matheus Figueiredo Soares Mingote
Published: (2019-02-01)

INFLUENCE OF SOMATIC MUTATIONS OF KRAS, NRAS, BRAF AND MICROSATELLITE INSTABILITY STATUS ON SURVIVAL OF COLORECTAL CANCER PATIENTS WITH PERITONAL CARCINO
by: V. P. Shubin, et al.
Published: (2020-10-01)

The role of MLH1, MSH2 and MSH6 in the development of colorectal cancer in Uganda
by: Richard Wismayer, et al.
Published: (2025-04-01)

Evaluation of Microsatellite Instability via High-Resolution Melt Analysis in Colorectal Carcinomas
by: Thais Maloberti, et al.
Published: (2024-11-01)

Sensitivity Assessment of Atmospheric Corrections for Clear and Moderately Turbid Optical Waters
by: Shahira Abdul Lathif, et al.
Published: (2025-01-01)

Single Center Characterization of a Cohort of Salivary Gland Carcinomas
by: Ria Winkelmann, et al.
Published: (2024-08-01)

HOXC6 promotes the metastasis of MSI-H CRC by interacting with M2 macrophages and inducing effector T cell exhaustion
by: Lina Qi, et al.
Published: (2025-04-01)

Monitoring active fires in Borneo from Sentinel-2 MSI images
by: Xiaoxiao Guo, et al.
Published: (2025-12-01)

Progressive Conditional Diffusion Model for Multistage Spectral Restoration of Remote Sensing Image
by: Jinfeng Gao, et al.
Published: (2025-01-01)

Seasonal cycles of snow algal blooms intensify surface melting on Antarctic ice shelves
by: Dong Liang, et al.
Published: (2025-07-01)

The effect of Entamoeba histolytica lectin antigen and microRNA-643 on the development of microsatellite instability (MSI) in colorectal adenocarcinoma
by: Leila Haghighi, et al.
Published: (2025-04-01)