Effect of Solvent on Protonation Equilibria of L-Proline and L-Valine in 1, 2-Propanediol-Water Mixtures

Protonation equilibria of L-proline and L-valine in varying compositions (0.0-60.0% v/v) of 1, 2-Propanediol-water mixtures were investigated pH-metrically. Titrations were performed at 303.0 K and the ionic strength of the medium was maintained at 0.16 mol L-1 using sodium chloride. The best fit ch...

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Bibliographic Details
Main Authors: P. Bhushanavathi, B. Veeraswamy, G. Nageswara Rao, U. Viplavaprasad
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/289074
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Summary:Protonation equilibria of L-proline and L-valine in varying compositions (0.0-60.0% v/v) of 1, 2-Propanediol-water mixtures were investigated pH-metrically. Titrations were performed at 303.0 K and the ionic strength of the medium was maintained at 0.16 mol L-1 using sodium chloride. The best fit chemical models of the protonation equilibria were based on crystallographic R-factor, Χ2, skewness, and kurtosis. All the protonation constants of proline and valine increased with increasing propanediol content. This is attributed to the dielectric constant of the medium.
ISSN:0973-4945
2090-9810