Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K
Experimental determination on solubility of deferiprone in propylene glycol + 1-propanol mixtures and their saturated solution's densities were reported at atmospheric pressure (101 kPa) from 293.2 to 313.2 K. In general, the solubility of deferiprone increases with the increase in temperature...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Chemical Thermodynamics and Thermal Analysis |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667312624000324 |
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| author | Homa Rezaei Elaheh Rahimpour Abolghasem Jouyban |
| author_facet | Homa Rezaei Elaheh Rahimpour Abolghasem Jouyban |
| author_sort | Homa Rezaei |
| collection | DOAJ |
| description | Experimental determination on solubility of deferiprone in propylene glycol + 1-propanol mixtures and their saturated solution's densities were reported at atmospheric pressure (101 kPa) from 293.2 to 313.2 K. In general, the solubility of deferiprone increases with the increase in temperature and concentration of propylene glycol in the mixtures. Dependence of solubility on composition and temperature were evaluated by fitting the experimental data to the double log-log, Jouyban-Acree-van't Hoff, modified Wilson and Jouyban-Acree equations, which showed that the latter equation represented the best mathematical description. Additionally, functions including the apparent standard dissolution Gibbs energy (ΔG°), standard dissolution enthalpy (ΔH°) and standard dissolution entropy change (ΔS°) were determined in order to provide basic knowledge on thermodynamics of deferiprone’ crystallization and industrial separation. |
| format | Article |
| id | doaj-art-d4761c39c5cf46b38f4870270b1258cc |
| institution | Kabale University |
| issn | 2667-3126 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Chemical Thermodynamics and Thermal Analysis |
| spelling | doaj-art-d4761c39c5cf46b38f4870270b1258cc2025-02-10T04:35:27ZengElsevierChemical Thermodynamics and Thermal Analysis2667-31262025-03-0117100159Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 KHoma Rezaei0Elaheh Rahimpour1Abolghasem Jouyban2Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranPharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranCorresponding author.; Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranExperimental determination on solubility of deferiprone in propylene glycol + 1-propanol mixtures and their saturated solution's densities were reported at atmospheric pressure (101 kPa) from 293.2 to 313.2 K. In general, the solubility of deferiprone increases with the increase in temperature and concentration of propylene glycol in the mixtures. Dependence of solubility on composition and temperature were evaluated by fitting the experimental data to the double log-log, Jouyban-Acree-van't Hoff, modified Wilson and Jouyban-Acree equations, which showed that the latter equation represented the best mathematical description. Additionally, functions including the apparent standard dissolution Gibbs energy (ΔG°), standard dissolution enthalpy (ΔH°) and standard dissolution entropy change (ΔS°) were determined in order to provide basic knowledge on thermodynamics of deferiprone’ crystallization and industrial separation.http://www.sciencedirect.com/science/article/pii/S2667312624000324SolubilityDeferiprone1-propanolPropylene glycol, binary solvent mixturesCosolvency modelsThermodynamics |
| spellingShingle | Homa Rezaei Elaheh Rahimpour Abolghasem Jouyban Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K Chemical Thermodynamics and Thermal Analysis Solubility Deferiprone 1-propanol Propylene glycol, binary solvent mixtures Cosolvency models Thermodynamics |
| title | Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K |
| title_full | Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K |
| title_fullStr | Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K |
| title_full_unstemmed | Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K |
| title_short | Solubility data of deferiprone in propylene glycol and 1-propanol mixtures at 293.2–323.2 K |
| title_sort | solubility data of deferiprone in propylene glycol and 1 propanol mixtures at 293 2 323 2 k |
| topic | Solubility Deferiprone 1-propanol Propylene glycol, binary solvent mixtures Cosolvency models Thermodynamics |
| url | http://www.sciencedirect.com/science/article/pii/S2667312624000324 |
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