Mapping hard tissue maturation: the role of Gallego stain in differential staining

Histological stains are specific dyes that attach to different tissues and are used in conjunction with hematoxylin and eosin stains in routine histopathology to provide useful information on tissues. With the usual stains, it becomes difficult to distinguish between the different hard tissues prese...

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Main Authors: Shweta Mary Reddy, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Oral Biology and Craniofacial Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212426825001198
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author Shweta Mary Reddy
Suganya Panneer Selvam
Ramya Ramadoss
Sandhya Sundar
author_facet Shweta Mary Reddy
Suganya Panneer Selvam
Ramya Ramadoss
Sandhya Sundar
author_sort Shweta Mary Reddy
collection DOAJ
description Histological stains are specific dyes that attach to different tissues and are used in conjunction with hematoxylin and eosin stains in routine histopathology to provide useful information on tissues. With the usual stains, it becomes difficult to distinguish between the different hard tissues present in oral pathological disorders. As one of the differential stains to discriminate between the hard tissues, modified Gallego's stain can be utilized. Maxilla and mandible of a 3-day-old rabbit are collected, followed by processing and embedding of the tissues, thin paraffin sections were made & stained with Modified Gallego's, and then viewed under the microscope. In the developing tooth germ, Dentin is stained green, and enamel is stained red in Modified Gallego staining. Modified Gallego staining facilitated the identification of the characteristics of hard and soft tissues during development and the changes in their behavior during maturation.
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publishDate 2025-07-01
publisher Elsevier
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series Journal of Oral Biology and Craniofacial Research
spelling doaj-art-d4761b315d584dcba479bc4abbeb464d2025-08-20T03:23:29ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682025-07-0115485886310.1016/j.jobcr.2025.06.004Mapping hard tissue maturation: the role of Gallego stain in differential stainingShweta Mary Reddy0Suganya Panneer Selvam1Ramya Ramadoss2Sandhya Sundar3Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, IndiaCorresponding author. Department of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.; Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, IndiaHistological stains are specific dyes that attach to different tissues and are used in conjunction with hematoxylin and eosin stains in routine histopathology to provide useful information on tissues. With the usual stains, it becomes difficult to distinguish between the different hard tissues present in oral pathological disorders. As one of the differential stains to discriminate between the hard tissues, modified Gallego's stain can be utilized. Maxilla and mandible of a 3-day-old rabbit are collected, followed by processing and embedding of the tissues, thin paraffin sections were made & stained with Modified Gallego's, and then viewed under the microscope. In the developing tooth germ, Dentin is stained green, and enamel is stained red in Modified Gallego staining. Modified Gallego staining facilitated the identification of the characteristics of hard and soft tissues during development and the changes in their behavior during maturation.http://www.sciencedirect.com/science/article/pii/S2212426825001198BoneCartilageCollagenDentinEnamelTooth germ
spellingShingle Shweta Mary Reddy
Suganya Panneer Selvam
Ramya Ramadoss
Sandhya Sundar
Mapping hard tissue maturation: the role of Gallego stain in differential staining
Journal of Oral Biology and Craniofacial Research
Bone
Cartilage
Collagen
Dentin
Enamel
Tooth germ
title Mapping hard tissue maturation: the role of Gallego stain in differential staining
title_full Mapping hard tissue maturation: the role of Gallego stain in differential staining
title_fullStr Mapping hard tissue maturation: the role of Gallego stain in differential staining
title_full_unstemmed Mapping hard tissue maturation: the role of Gallego stain in differential staining
title_short Mapping hard tissue maturation: the role of Gallego stain in differential staining
title_sort mapping hard tissue maturation the role of gallego stain in differential staining
topic Bone
Cartilage
Collagen
Dentin
Enamel
Tooth germ
url http://www.sciencedirect.com/science/article/pii/S2212426825001198
work_keys_str_mv AT shwetamaryreddy mappinghardtissuematurationtheroleofgallegostainindifferentialstaining
AT suganyapanneerselvam mappinghardtissuematurationtheroleofgallegostainindifferentialstaining
AT ramyaramadoss mappinghardtissuematurationtheroleofgallegostainindifferentialstaining
AT sandhyasundar mappinghardtissuematurationtheroleofgallegostainindifferentialstaining