Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials
Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects...
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| Language: | English |
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Korean College of Helicobacter and Upper Gastrointestinal Research
2018-12-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.247 |
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| author | Young-Jae Hwang Nayoung Kim Sung Eun Kim Gwang Ho Baik Ju Yup Lee Kyung Sik Park Young-Eun Joo Dae-Seong Myung Hyeon Ju Kim Hyun Joo Song Heung Up Kim Kwangwoo Nam Jeong Eun Shin Hyun Jin Kim Gwang Ha Kim Jongchan Lee Seon Hee Lim Geom Seog Seo Suck Chei Choi |
| author_facet | Young-Jae Hwang Nayoung Kim Sung Eun Kim Gwang Ho Baik Ju Yup Lee Kyung Sik Park Young-Eun Joo Dae-Seong Myung Hyeon Ju Kim Hyun Joo Song Heung Up Kim Kwangwoo Nam Jeong Eun Shin Hyun Jin Kim Gwang Ha Kim Jongchan Lee Seon Hee Lim Geom Seog Seo Suck Chei Choi |
| author_sort | Young-Jae Hwang |
| collection | DOAJ |
| description | Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016∼2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016∼2017 (51.6%; 1,293/2,506; P＜ 0.001). The prevalence of AG decreased from 2011 to 2016∼2017 (P=0.018), but that of IM increased (P＜ 0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016∼2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016∼2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016∼2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection. |
| format | Article |
| id | doaj-art-d467ae88ffc94b24ae7597dc91293f40 |
| institution | DOAJ |
| issn | 1738-3331 |
| language | English |
| publishDate | 2018-12-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-d467ae88ffc94b24ae7597dc91293f402025-08-20T02:51:25ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312018-12-0118424725710.7704/kjhugr.2018.18.4.247kjhugr.2018.18.4.247Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical TrialsYoung-Jae Hwang0Nayoung Kim1Sung Eun Kim2Gwang Ho Baik3Ju Yup Lee4Kyung Sik Park5Young-Eun Joo6Dae-Seong Myung7Hyeon Ju Kim8Hyun Joo Song9Heung Up Kim10Kwangwoo Nam11Jeong Eun Shin12Hyun Jin Kim13Gwang Ha Kim14Jongchan Lee15Seon Hee Lim16Geom Seog Seo17Suck Chei Choi18Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDepartment of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDepartment of Internal Medicine, College of Medicine, Hallym University, Chuncheon, KoreaDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, KoreaDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, KoreaDepartment of Family Medicine, Jeju National University School of Medicine, Jeju, KoreaDepartment of Internal Medicine, Jeju National University School of Medicine, Jeju, KoreaDepartment of Internal Medicine, Jeju National University School of Medicine, Jeju, KoreaDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan, KoreaDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan, KoreaDepartment of Internal Medicine and Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, KoreaDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDepartment of Internal Medicine, Seoul National University Healthcare System Gangnam Center and Healthcare Research Institute, Seoul, KoreaDepartment of Internal Medicine, Wonkwang University School of Medicine, Iksan, KoreaDepartment of Internal Medicine, Wonkwang University School of Medicine, Iksan, KoreaBackground/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016∼2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016∼2017 (51.6%; 1,293/2,506; P＜ 0.001). The prevalence of AG decreased from 2011 to 2016∼2017 (P=0.018), but that of IM increased (P＜ 0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016∼2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016∼2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016∼2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.247Atrophic gastritisHelicobacter pyloriMetaplasiaPrevalenceRisk factors |
| spellingShingle | Young-Jae Hwang Nayoung Kim Sung Eun Kim Gwang Ho Baik Ju Yup Lee Kyung Sik Park Young-Eun Joo Dae-Seong Myung Hyeon Ju Kim Hyun Joo Song Heung Up Kim Kwangwoo Nam Jeong Eun Shin Hyun Jin Kim Gwang Ha Kim Jongchan Lee Seon Hee Lim Geom Seog Seo Suck Chei Choi Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials The Korean Journal of Helicobacter and Upper Gastrointestinal Research Atrophic gastritis Helicobacter pylori Metaplasia Prevalence Risk factors |
| title | Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials |
| title_full | Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials |
| title_fullStr | Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials |
| title_full_unstemmed | Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials |
| title_short | Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials |
| title_sort | change in the prevalences and risk factors of atrophic gastritis and intestinal metaplasia in korea multicenter clinical trials |
| topic | Atrophic gastritis Helicobacter pylori Metaplasia Prevalence Risk factors |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.247 |
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