Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials

Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials

Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects...

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Main Authors: Young-Jae Hwang, Nayoung Kim, Sung Eun Kim, Gwang Ho Baik, Ju Yup Lee, Kyung Sik Park, Young-Eun Joo, Dae-Seong Myung, Hyeon Ju Kim, Hyun Joo Song, Heung Up Kim, Kwangwoo Nam, Jeong Eun Shin, Hyun Jin Kim, Gwang Ha Kim, Jongchan Lee, Seon Hee Lim, Geom Seog Seo, Suck Chei Choi
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2018-12-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Atrophic gastritis
Helicobacter pylori
Metaplasia
Prevalence
Risk factors
Online Access:http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.247
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Summary:Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016∼2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016∼2017 (51.6%; 1,293/2,506; P＜ 0.001). The prevalence of AG decreased from 2011 to 2016∼2017 (P=0.018), but that of IM increased (P＜ 0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016∼2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016∼2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016∼2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.
ISSN:1738-3331

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