BACTERIOCINS OF Lactobacillus LF221 STRAIN

LF221 strain is a Lactobacillus isolate from a baby’s faeces that was previously found to produce bacteriocin(s) with inhibitory activity against a wide range of bacterial species including some pathogenic and food-spoilage (Bacillus cereus, Clostridium sp., Listeria innocua, Staphylococcus aureus)....

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Main Authors: Bojana BOGOVIČ MATIJAŠIĆ, Irena ROGELJ
Format: Article
Language:English
Published: University of Ljubljana Press (Založba Univerze v Ljubljani) 1998-12-01
Series:Acta Agriculturae Slovenica
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Online Access:https://journals.uni-lj.si/aas/article/view/17081
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author Bojana BOGOVIČ MATIJAŠIĆ
Irena ROGELJ
author_facet Bojana BOGOVIČ MATIJAŠIĆ
Irena ROGELJ
author_sort Bojana BOGOVIČ MATIJAŠIĆ
collection DOAJ
description LF221 strain is a Lactobacillus isolate from a baby’s faeces that was previously found to produce bacteriocin(s) with inhibitory activity against a wide range of bacterial species including some pathogenic and food-spoilage (Bacillus cereus, Clostridium sp., Listeria innocua, Staphylococcus aureus). Isoelectric point and molecular mass of bacteriocin complex and subunits were estimated. Precipitation with ammonium sulphate, cation exchange chromatography, C8 hydrophobic interaction chromatography and reverse-phase FPLC chromatography were used to isolate bacteriocins from the supernatant of MRS culture. Amino acid composition and partial N-terminal amino acid sequences of two isolated bacteriocins were determined. Bacteriocins were present in MRS supernatant as aggregates with Mw>150.000 and pI 5.1-5.3, while Mw of subunits was 3500-5000. A high content of glycin and alanin was observed for both bacteriocins. The N-terminal amino acid sequences showed little similarity with those of other bacteriocins. Acidocins LF221 A and B appear to belong to the II class of LAB bacteriocins.
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publishDate 1998-12-01
publisher University of Ljubljana Press (Založba Univerze v Ljubljani)
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series Acta Agriculturae Slovenica
spelling doaj-art-d462b3edfcd3402f9a77c9f43209c0c62025-08-20T02:57:37ZengUniversity of Ljubljana Press (Založba Univerze v Ljubljani)Acta Agriculturae Slovenica1854-19411998-12-0172111312110.14720/aas.1998.72.1.1708123475BACTERIOCINS OF Lactobacillus LF221 STRAINBojana BOGOVIČ MATIJAŠIĆ0Irena ROGELJ1Univ. of Ljubljana, Biotechnical Fac., Zootechnical Dept., Groblje 3, SI-1230 Domžale, SloveniaUniv. of Ljubljana, Biotechnical Fac., Zootechnical Dept., Groblje 3, SI-1230 Domžale, SloveniaLF221 strain is a Lactobacillus isolate from a baby’s faeces that was previously found to produce bacteriocin(s) with inhibitory activity against a wide range of bacterial species including some pathogenic and food-spoilage (Bacillus cereus, Clostridium sp., Listeria innocua, Staphylococcus aureus). Isoelectric point and molecular mass of bacteriocin complex and subunits were estimated. Precipitation with ammonium sulphate, cation exchange chromatography, C8 hydrophobic interaction chromatography and reverse-phase FPLC chromatography were used to isolate bacteriocins from the supernatant of MRS culture. Amino acid composition and partial N-terminal amino acid sequences of two isolated bacteriocins were determined. Bacteriocins were present in MRS supernatant as aggregates with Mw>150.000 and pI 5.1-5.3, while Mw of subunits was 3500-5000. A high content of glycin and alanin was observed for both bacteriocins. The N-terminal amino acid sequences showed little similarity with those of other bacteriocins. Acidocins LF221 A and B appear to belong to the II class of LAB bacteriocins.https://journals.uni-lj.si/aas/article/view/17081microbiologybacterialactobacillusbacteriocinsclassification
spellingShingle Bojana BOGOVIČ MATIJAŠIĆ
Irena ROGELJ
BACTERIOCINS OF Lactobacillus LF221 STRAIN
Acta Agriculturae Slovenica
microbiology
bacteria
lactobacillus
bacteriocins
classification
title BACTERIOCINS OF Lactobacillus LF221 STRAIN
title_full BACTERIOCINS OF Lactobacillus LF221 STRAIN
title_fullStr BACTERIOCINS OF Lactobacillus LF221 STRAIN
title_full_unstemmed BACTERIOCINS OF Lactobacillus LF221 STRAIN
title_short BACTERIOCINS OF Lactobacillus LF221 STRAIN
title_sort bacteriocins of lactobacillus lf221 strain
topic microbiology
bacteria
lactobacillus
bacteriocins
classification
url https://journals.uni-lj.si/aas/article/view/17081
work_keys_str_mv AT bojanabogovicmatijasic bacteriocinsoflactobacilluslf221strain
AT irenarogelj bacteriocinsoflactobacilluslf221strain