Modern opportunities of regenerative medicine: biofabrication of hollow organs
For the treatment of patients with organs damaged or removed by medical indications, transplantation from donors is currently used. High risks of death, lifelong immunosuppression and an acute shortage of donor organs worsen the prospect of their use. Recent advances in the field of biofabrication i...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2019-07-01
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| Series: | Вестник трансплантологии и искусственных органов |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/1025 |
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| author | E. S. Evstratova P. V. Shegay S. V. Popov N. V. Vorobyev S. A. Ivanov А. D. Kaprin |
| author_facet | E. S. Evstratova P. V. Shegay S. V. Popov N. V. Vorobyev S. A. Ivanov А. D. Kaprin |
| author_sort | E. S. Evstratova |
| collection | DOAJ |
| description | For the treatment of patients with organs damaged or removed by medical indications, transplantation from donors is currently used. High risks of death, lifelong immunosuppression and an acute shortage of donor organs worsen the prospect of their use. Recent advances in the field of biofabrication indicate the imminent possibility of the emergence of real alternatives to the methods currently used. The biomaterials used create a three-dimensional space in which cells can attach, grow and form new tissues with an appropriate structure and function. Modern research pays special attention to the choice of materials and technologies to ensure the mechanical and physiological properties of the newly created tissue. The review examines modem technologies of regenerative medicine, as well as the results of experimental studies in the field of biofabrication for creating scaffolds, tissue-engineering structures, as well as hollow and fragments of complex organs that already have practical implementation. |
| format | Article |
| id | doaj-art-d45f710f686e42008fbf2fb80365d322 |
| institution | DOAJ |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2019-07-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-d45f710f686e42008fbf2fb80365d3222025-08-20T03:21:06ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912019-07-012129210310.15825/1995-1191-2019-2-92-103788Modern opportunities of regenerative medicine: biofabrication of hollow organsE. S. Evstratova0P. V. Shegay1S. V. Popov2N. V. Vorobyev3S. A. Ivanov4А. D. Kaprin5National Medical Research Radiological Center of the Ministry of Health of the Russian FederationNational Medical Research Radiological Center of the Ministry of Health of the Russian Federation; Peoples' Friendship University of Russia of the Ministry of Education and Science of the Russian FederationPeoples' Friendship University of Russia of the Ministry of Education and Science of the Russian FederationP.A. Hertsen Moscow Oncology Research Center - branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian FederationA. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation; Peoples' Friendship University of Russia of the Ministry of Education and Science of the Russian FederationNational Medical Research Radiological Center of the Ministry of Health of the Russian Federation; P.A. Hertsen Moscow Oncology Research Center - branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation; Peoples' Friendship University of Russia of the Ministry of Education and Science of the Russian FederationFor the treatment of patients with organs damaged or removed by medical indications, transplantation from donors is currently used. High risks of death, lifelong immunosuppression and an acute shortage of donor organs worsen the prospect of their use. Recent advances in the field of biofabrication indicate the imminent possibility of the emergence of real alternatives to the methods currently used. The biomaterials used create a three-dimensional space in which cells can attach, grow and form new tissues with an appropriate structure and function. Modern research pays special attention to the choice of materials and technologies to ensure the mechanical and physiological properties of the newly created tissue. The review examines modem technologies of regenerative medicine, as well as the results of experimental studies in the field of biofabrication for creating scaffolds, tissue-engineering structures, as well as hollow and fragments of complex organs that already have practical implementation.https://journal.transpl.ru/vtio/article/view/1025regenerative medicinestem cellsbladderuterushollow organsbiotechnologytissue engineeringbiofabrication |
| spellingShingle | E. S. Evstratova P. V. Shegay S. V. Popov N. V. Vorobyev S. A. Ivanov А. D. Kaprin Modern opportunities of regenerative medicine: biofabrication of hollow organs Вестник трансплантологии и искусственных органов regenerative medicine stem cells bladder uterus hollow organs biotechnology tissue engineering biofabrication |
| title | Modern opportunities of regenerative medicine: biofabrication of hollow organs |
| title_full | Modern opportunities of regenerative medicine: biofabrication of hollow organs |
| title_fullStr | Modern opportunities of regenerative medicine: biofabrication of hollow organs |
| title_full_unstemmed | Modern opportunities of regenerative medicine: biofabrication of hollow organs |
| title_short | Modern opportunities of regenerative medicine: biofabrication of hollow organs |
| title_sort | modern opportunities of regenerative medicine biofabrication of hollow organs |
| topic | regenerative medicine stem cells bladder uterus hollow organs biotechnology tissue engineering biofabrication |
| url | https://journal.transpl.ru/vtio/article/view/1025 |
| work_keys_str_mv | AT esevstratova modernopportunitiesofregenerativemedicinebiofabricationofholloworgans AT pvshegay modernopportunitiesofregenerativemedicinebiofabricationofholloworgans AT svpopov modernopportunitiesofregenerativemedicinebiofabricationofholloworgans AT nvvorobyev modernopportunitiesofregenerativemedicinebiofabricationofholloworgans AT saivanov modernopportunitiesofregenerativemedicinebiofabricationofholloworgans AT adkaprin modernopportunitiesofregenerativemedicinebiofabricationofholloworgans |