Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences

Background and aim: While conventional MS rehabilitation primarily addresses physical and cognitive symptoms, recent advances in VR technology offer immersive environments that facilitate both emotional and cognitive skill development. The purpose of this study is to evaluate the impact of VR-based...

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Main Authors: Maria Grazia Maggio, Alessandra Benenati, Federica Impellizzeri, Amelia Rizzo, Martina Barbera, Antonino Cannavò, Vera Gregoli, Giovanni Morone, Francesco Chirico, Angelo Quartarone, Rocco Salvatore Calabrò
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Brain Sciences
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Online Access:https://www.mdpi.com/2076-3425/14/12/1227
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author Maria Grazia Maggio
Alessandra Benenati
Federica Impellizzeri
Amelia Rizzo
Martina Barbera
Antonino Cannavò
Vera Gregoli
Giovanni Morone
Francesco Chirico
Angelo Quartarone
Rocco Salvatore Calabrò
author_facet Maria Grazia Maggio
Alessandra Benenati
Federica Impellizzeri
Amelia Rizzo
Martina Barbera
Antonino Cannavò
Vera Gregoli
Giovanni Morone
Francesco Chirico
Angelo Quartarone
Rocco Salvatore Calabrò
author_sort Maria Grazia Maggio
collection DOAJ
description Background and aim: While conventional MS rehabilitation primarily addresses physical and cognitive symptoms, recent advances in VR technology offer immersive environments that facilitate both emotional and cognitive skill development. The purpose of this study is to evaluate the impact of VR-based training on emotional self-efficacy in multiple sclerosis (MS) patients and examine its association with cognitive function improvement. Additionally, this study aims to explore potential gender differences in these outcomes, hypothesizing that gender may influence the effectiveness of VR-based rehabilitation, which could inform more tailored approaches for emotional and cognitive rehabilitation in MS. Method: The present retrospective study analyzed data from 43 MS patients undergoing cognitive and behavioral rehabilitation at the IRCCS Centro Neurolesi “Bonino Pulejo” in Italy, comparing a VR intervention group (VR-G) and a control group receiving traditional rehabilitation. Emotional self-efficacy, depression, and anxiety were assessed, alongside cognitive function pre- and post-intervention. Results: Findings indicate that the VR-G showed significant improvements in managing negative emotions, reduced depressive and anxiety symptoms, and enhanced cognitive performance, particularly in verbal learning and working memory. Gender-based analysis revealed a trend suggesting that females in the VR-G may exhibit greater improvements in positive emotional self-efficacy, although this difference did not reach statistical significance. Spearman’s correlation highlighted associations between emotional self-efficacy and cognitive gains, supporting the potential of VR to foster both emotional and cognitive resilience. Conclusions: These findings suggest that VR training may provide a tailored approach for MS rehabilitation, enhancing therapeutic outcomes by integrating emotional and cognitive training in an immersive setting. Further research should investigate long-term effects and neurophysiological correlates of VR training to optimize MS rehabilitation.
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spelling doaj-art-d4598cdaad9748a49d30dbdd83e1f75e2025-08-20T02:56:06ZengMDPI AGBrain Sciences2076-34252024-12-011412122710.3390/brainsci14121227Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender DifferencesMaria Grazia Maggio0Alessandra Benenati1Federica Impellizzeri2Amelia Rizzo3Martina Barbera4Antonino Cannavò5Vera Gregoli6Giovanni Morone7Francesco Chirico8Angelo Quartarone9Rocco Salvatore Calabrò10IRCCS Centro Neurolesi Bonino-Pulejo, 98124 Messina, ItalyDepartment of Psychology “Renzo Canestrari”, University of Bologna, Via Zamboni, 33, 40126 Bologna, ItalyIRCCS Centro Neurolesi Bonino-Pulejo, 98124 Messina, ItalyDepartment of Clinical and Experimental Medicine, University of Messina, Piazza Pugliatti, 1, 98122 Messina, ItalyDepartment of Clinical and Experimental Medicine, University of Messina, Piazza Pugliatti, 1, 98122 Messina, ItalyA.O.U. Policlinico “G. Martino”, Via Consolare Valeria, 98124 Messina, ItalyDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Via Cracovia, 90, 00133 Roma, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyPost-Graduate School of Occupational Medicine, Università Cattolica del Sacro Cuore, 00168 Rome, ItalyIRCCS Centro Neurolesi Bonino-Pulejo, 98124 Messina, ItalyIRCCS Centro Neurolesi Bonino-Pulejo, 98124 Messina, ItalyBackground and aim: While conventional MS rehabilitation primarily addresses physical and cognitive symptoms, recent advances in VR technology offer immersive environments that facilitate both emotional and cognitive skill development. The purpose of this study is to evaluate the impact of VR-based training on emotional self-efficacy in multiple sclerosis (MS) patients and examine its association with cognitive function improvement. Additionally, this study aims to explore potential gender differences in these outcomes, hypothesizing that gender may influence the effectiveness of VR-based rehabilitation, which could inform more tailored approaches for emotional and cognitive rehabilitation in MS. Method: The present retrospective study analyzed data from 43 MS patients undergoing cognitive and behavioral rehabilitation at the IRCCS Centro Neurolesi “Bonino Pulejo” in Italy, comparing a VR intervention group (VR-G) and a control group receiving traditional rehabilitation. Emotional self-efficacy, depression, and anxiety were assessed, alongside cognitive function pre- and post-intervention. Results: Findings indicate that the VR-G showed significant improvements in managing negative emotions, reduced depressive and anxiety symptoms, and enhanced cognitive performance, particularly in verbal learning and working memory. Gender-based analysis revealed a trend suggesting that females in the VR-G may exhibit greater improvements in positive emotional self-efficacy, although this difference did not reach statistical significance. Spearman’s correlation highlighted associations between emotional self-efficacy and cognitive gains, supporting the potential of VR to foster both emotional and cognitive resilience. Conclusions: These findings suggest that VR training may provide a tailored approach for MS rehabilitation, enhancing therapeutic outcomes by integrating emotional and cognitive training in an immersive setting. Further research should investigate long-term effects and neurophysiological correlates of VR training to optimize MS rehabilitation.https://www.mdpi.com/2076-3425/14/12/1227multiple sclerosisneurorehabilitationvirtual realityemotional self-efficacycognitive rehabilitationgender differences
spellingShingle Maria Grazia Maggio
Alessandra Benenati
Federica Impellizzeri
Amelia Rizzo
Martina Barbera
Antonino Cannavò
Vera Gregoli
Giovanni Morone
Francesco Chirico
Angelo Quartarone
Rocco Salvatore Calabrò
Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
Brain Sciences
multiple sclerosis
neurorehabilitation
virtual reality
emotional self-efficacy
cognitive rehabilitation
gender differences
title Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
title_full Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
title_fullStr Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
title_full_unstemmed Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
title_short Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences
title_sort impact of cognitive vr vs traditional training on emotional self efficacy and cognitive function in patients with multiple sclerosis a retrospective study focusing on gender differences
topic multiple sclerosis
neurorehabilitation
virtual reality
emotional self-efficacy
cognitive rehabilitation
gender differences
url https://www.mdpi.com/2076-3425/14/12/1227
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