Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study
The effect of some drugs, inducing vasodilatation, was noted on skin flap survival in rats, 6-hydroxydopamine, which induces chemical sympathectomy, produced marked survival of the flaps. Isoxsuprine and salbutamol, the beta-2 receptor agonists, also induced significant augmentation of flap survival...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
1984-12-01
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| Series: | Indian Journal of Plastic Surgery |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778490 |
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| author | V. Bhattacharya S. K. Bhattacharya J. M. Das J. K. Sinha F. M. Tripathi |
| author_facet | V. Bhattacharya S. K. Bhattacharya J. M. Das J. K. Sinha F. M. Tripathi |
| author_sort | V. Bhattacharya |
| collection | DOAJ |
| description | The effect of some drugs, inducing vasodilatation, was noted on skin flap survival in rats, 6-hydroxydopamine, which induces chemical sympathectomy, produced marked survival of the flaps. Isoxsuprine and salbutamol, the beta-2 receptor agonists, also induced significant augmentation of flap survival. All these drugs were more cffective than the surgical delay procedure. Reserpine didnot enhance skin flap survival, Since 6-HD, isoxsuprine and salbutamol produce marked vasodilatation, they may prevent skin flap necrosis by enhancing cutaneous blood flow. |
| format | Article |
| id | doaj-art-d450f14f8a2941bf8fe691bdfc877a12 |
| institution | OA Journals |
| issn | 0970-0358 1998-376X |
| language | English |
| publishDate | 1984-12-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj-art-d450f14f8a2941bf8fe691bdfc877a122025-08-20T02:03:40ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03581998-376X1984-12-011702414510.1055/s-0043-1778490Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental StudyV. Bhattacharya0S. K. Bhattacharya1J. M. Das2J. K. Sinha3F. M. Tripathi4Division of Plastic Surgery, Depariment of Surgery, Institute of Medical Sciences, Banaras Hindu Usiversity, Varanasi, IndiaDivision of Plastic Surgery, Depariment of Surgery, Institute of Medical Sciences, Banaras Hindu Usiversity, Varanasi, IndiaDivision of Plastic Surgery, Depariment of Surgery, Institute of Medical Sciences, Banaras Hindu Usiversity, Varanasi, IndiaDivision of Plastic Surgery, Depariment of Surgery, Institute of Medical Sciences, Banaras Hindu Usiversity, Varanasi, IndiaDivision of Plastic Surgery, Depariment of Surgery, Institute of Medical Sciences, Banaras Hindu Usiversity, Varanasi, IndiaThe effect of some drugs, inducing vasodilatation, was noted on skin flap survival in rats, 6-hydroxydopamine, which induces chemical sympathectomy, produced marked survival of the flaps. Isoxsuprine and salbutamol, the beta-2 receptor agonists, also induced significant augmentation of flap survival. All these drugs were more cffective than the surgical delay procedure. Reserpine didnot enhance skin flap survival, Since 6-HD, isoxsuprine and salbutamol produce marked vasodilatation, they may prevent skin flap necrosis by enhancing cutaneous blood flow.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778490 |
| spellingShingle | V. Bhattacharya S. K. Bhattacharya J. M. Das J. K. Sinha F. M. Tripathi Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study Indian Journal of Plastic Surgery |
| title | Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study |
| title_full | Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study |
| title_fullStr | Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study |
| title_full_unstemmed | Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study |
| title_short | Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study |
| title_sort | augmentation effect of certain vasodilators on skin flap viability an experimental study |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778490 |
| work_keys_str_mv | AT vbhattacharya augmentationeffectofcertainvasodilatorsonskinflapviabilityanexperimentalstudy AT skbhattacharya augmentationeffectofcertainvasodilatorsonskinflapviabilityanexperimentalstudy AT jmdas augmentationeffectofcertainvasodilatorsonskinflapviabilityanexperimentalstudy AT jksinha augmentationeffectofcertainvasodilatorsonskinflapviabilityanexperimentalstudy AT fmtripathi augmentationeffectofcertainvasodilatorsonskinflapviabilityanexperimentalstudy |