Augmentation Effect of Certain Vasodilators on Skin Flap Viability—An Experimental Study
The effect of some drugs, inducing vasodilatation, was noted on skin flap survival in rats, 6-hydroxydopamine, which induces chemical sympathectomy, produced marked survival of the flaps. Isoxsuprine and salbutamol, the beta-2 receptor agonists, also induced significant augmentation of flap survival...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
1984-12-01
|
| Series: | Indian Journal of Plastic Surgery |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778490 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The effect of some drugs, inducing vasodilatation, was noted on skin flap survival in rats, 6-hydroxydopamine, which induces chemical sympathectomy, produced marked survival of the flaps. Isoxsuprine and salbutamol, the beta-2 receptor agonists, also induced significant augmentation of flap survival. All these drugs were more cffective than the surgical delay procedure. Reserpine didnot enhance skin flap survival, Since 6-HD, isoxsuprine and salbutamol produce marked vasodilatation, they may prevent skin flap necrosis by enhancing cutaneous blood flow. |
|---|---|
| ISSN: | 0970-0358 1998-376X |