At the crossroads of calcium signaling, protein synthesis and neuropeptide release

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

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Bibliographic Details
Main Authors: Jakob Rupert, Dragomir Milovanovic
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/106553
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author Jakob Rupert
Dragomir Milovanovic
author_facet Jakob Rupert
Dragomir Milovanovic
author_sort Jakob Rupert
collection DOAJ
description By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.
format Article
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institution DOAJ
issn 2050-084X
language English
publishDate 2025-04-01
publisher eLife Sciences Publications Ltd
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spelling doaj-art-d440ae4f57c24d7289fdfb61a2741fda2025-08-20T03:03:04ZengeLife Sciences Publications LtdeLife2050-084X2025-04-011410.7554/eLife.106553At the crossroads of calcium signaling, protein synthesis and neuropeptide releaseJakob Rupert0https://orcid.org/0000-0002-0879-1594Dragomir Milovanovic1https://orcid.org/0000-0002-6625-1879Laboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE), Berlin and Bonn, GermanyLaboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE), Berlin and Bonn, GermanyBy influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.https://elifesciences.org/articles/106553neuropeptideexocytosisRab10protein synthesisendoplasmic reticulumsynaptic transmission
spellingShingle Jakob Rupert
Dragomir Milovanovic
At the crossroads of calcium signaling, protein synthesis and neuropeptide release
eLife
neuropeptide
exocytosis
Rab10
protein synthesis
endoplasmic reticulum
synaptic transmission
title At the crossroads of calcium signaling, protein synthesis and neuropeptide release
title_full At the crossroads of calcium signaling, protein synthesis and neuropeptide release
title_fullStr At the crossroads of calcium signaling, protein synthesis and neuropeptide release
title_full_unstemmed At the crossroads of calcium signaling, protein synthesis and neuropeptide release
title_short At the crossroads of calcium signaling, protein synthesis and neuropeptide release
title_sort at the crossroads of calcium signaling protein synthesis and neuropeptide release
topic neuropeptide
exocytosis
Rab10
protein synthesis
endoplasmic reticulum
synaptic transmission
url https://elifesciences.org/articles/106553
work_keys_str_mv AT jakobrupert atthecrossroadsofcalciumsignalingproteinsynthesisandneuropeptiderelease
AT dragomirmilovanovic atthecrossroadsofcalciumsignalingproteinsynthesisandneuropeptiderelease