Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report

Abstract Background Duodenal carcinoma originating in Brunner’s gland is rare. Herein, we report a case of duodenal carcinoma arising from Brunner’s gland in a 63-year-old man. Case presentation On diagnostic imaging, the lesion presented as a non-invasive carcinoma; the patient also had uncontrolle...

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Main Authors: Tetsuya Mochizuki, Nobuaki Fujikuni, Koichi Nakadoi, Masahiro Nakahara, Kazuaki Tanabe, Shuji Yonehara, Toshio Noriyuki
Format: Article
Language:English
Published: Japan Surgical Society 2019-11-01
Series:Surgical Case Reports
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Online Access:http://link.springer.com/article/10.1186/s40792-019-0732-4
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author Tetsuya Mochizuki
Nobuaki Fujikuni
Koichi Nakadoi
Masahiro Nakahara
Kazuaki Tanabe
Shuji Yonehara
Toshio Noriyuki
author_facet Tetsuya Mochizuki
Nobuaki Fujikuni
Koichi Nakadoi
Masahiro Nakahara
Kazuaki Tanabe
Shuji Yonehara
Toshio Noriyuki
author_sort Tetsuya Mochizuki
collection DOAJ
description Abstract Background Duodenal carcinoma originating in Brunner’s gland is rare. Herein, we report a case of duodenal carcinoma arising from Brunner’s gland in a 63-year-old man. Case presentation On diagnostic imaging, the lesion presented as a non-invasive carcinoma; the patient also had uncontrolled diabetes and liver cirrhosis. Hence, we decided to perform partial duodenectomy to reduce operative stress. Pathological examination revealed that the tumor consisted of tissue from Brunner’s gland. Additionally, the carcinoma cells were strongly positive for Mucin-6 protein, which is an epithelial marker of Brunner’s gland. The patient’s post-operative course was uneventful, and he has been well for 2 years after the surgery. Conclusions This a rare case of an adenocarcinoma arising from Brunner’s gland of the duodenum that was resected by duodenectomy.
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institution DOAJ
issn 2198-7793
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publishDate 2019-11-01
publisher Japan Surgical Society
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series Surgical Case Reports
spelling doaj-art-d436ded7febd4bffa5656c551de029fc2025-08-20T03:18:09ZengJapan Surgical SocietySurgical Case Reports2198-77932019-11-01511510.1186/s40792-019-0732-4Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case reportTetsuya Mochizuki0Nobuaki Fujikuni1Koichi Nakadoi2Masahiro Nakahara3Kazuaki Tanabe4Shuji Yonehara5Toshio Noriyuki6Department of Surgery, Onomichi General HospitalDepartment of Surgery, Onomichi General HospitalDepartment of Gastroenterology, Onomichi General HospitalDepartment of Surgery, Onomichi General HospitalDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Pathology, Onomichi General HospitalDepartment of Surgery, Onomichi General HospitalAbstract Background Duodenal carcinoma originating in Brunner’s gland is rare. Herein, we report a case of duodenal carcinoma arising from Brunner’s gland in a 63-year-old man. Case presentation On diagnostic imaging, the lesion presented as a non-invasive carcinoma; the patient also had uncontrolled diabetes and liver cirrhosis. Hence, we decided to perform partial duodenectomy to reduce operative stress. Pathological examination revealed that the tumor consisted of tissue from Brunner’s gland. Additionally, the carcinoma cells were strongly positive for Mucin-6 protein, which is an epithelial marker of Brunner’s gland. The patient’s post-operative course was uneventful, and he has been well for 2 years after the surgery. Conclusions This a rare case of an adenocarcinoma arising from Brunner’s gland of the duodenum that was resected by duodenectomy.http://link.springer.com/article/10.1186/s40792-019-0732-4AdenocarcinomaBrunner’s glandDuodenal carcinoma
spellingShingle Tetsuya Mochizuki
Nobuaki Fujikuni
Koichi Nakadoi
Masahiro Nakahara
Kazuaki Tanabe
Shuji Yonehara
Toshio Noriyuki
Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
Surgical Case Reports
Adenocarcinoma
Brunner’s gland
Duodenal carcinoma
title Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
title_full Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
title_fullStr Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
title_full_unstemmed Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
title_short Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
title_sort adenocarcinoma of the duodenum arising from brunner s gland resected by partial duodenectomy a case report
topic Adenocarcinoma
Brunner’s gland
Duodenal carcinoma
url http://link.springer.com/article/10.1186/s40792-019-0732-4
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