Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study

Abstract Background Patient preferences have gradually been incorporated into decisions about cancer treatment regimens over recent years. Meanwhile, the efficacy of traditional Chinese medicine (TCM) in cancer-related treatments has been recognized. This study aimed to estimate the specific prefere...

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Main Authors: Jiao Zhang, Lihua Li, Huinan Xi, Qi Wang, Fan Jiang, Xin Sun, Xuebin Qiao, Aijun Xu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-025-04937-4
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author Jiao Zhang
Lihua Li
Huinan Xi
Qi Wang
Fan Jiang
Xin Sun
Xuebin Qiao
Aijun Xu
author_facet Jiao Zhang
Lihua Li
Huinan Xi
Qi Wang
Fan Jiang
Xin Sun
Xuebin Qiao
Aijun Xu
author_sort Jiao Zhang
collection DOAJ
description Abstract Background Patient preferences have gradually been incorporated into decisions about cancer treatment regimens over recent years. Meanwhile, the efficacy of traditional Chinese medicine (TCM) in cancer-related treatments has been recognized. This study aimed to estimate the specific preferences of cancer patients for TCM treatment regimens to inform the clinical decision-making process for health promotion. Methods This cross-sectional investigation employed a discrete choice experiment (DCE) methodology to assess TCM treatment regimens preferences among cancer patients. The DCE systematically elicits participants’ preferences through the sequential presentation of hypothetical clinical scenarios with varying combinations of therapeutic attributes, with subsequent data analysis conducted using mixed logit models. We applied this methodology to examine cancer patient preferences regarding different TCM treatment regimens. Additionally, a subgroup analysis of sex groups was conducted to identify potential preference variations across demographic groups. Results In total, 728 participants completed the questionnaire and passed the consistency test. Control rate of disease, gastrointestinal adverse effects, mode of administration, treatment duration, quality of life, and monthly out-of-pocket cost had a significant impact on the TCM treatment preference of the participating cancer patients. Preferences almost remained consistent irrespective of the participants’ sex. Conclusions Differences in treatment have an impact on the preferences of TCM treatment in cancer patients. Cancer patients' preferences related to the control rate of disease and quality of life should be prioritized and considered in TCM treatment decision-making.
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spelling doaj-art-d4350833d2ff4575a07c9b74b84afb4c2025-08-20T03:03:23ZengBMCBMC Complementary Medicine and Therapies2662-76712025-07-012511910.1186/s12906-025-04937-4Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment studyJiao Zhang0Lihua Li1Huinan Xi2Qi Wang3Fan Jiang4Xin Sun5Xuebin Qiao6Aijun Xu7School of Health Economics and Management, Nanjing University of Chinese MedicineSchool of Health Economics and Management, Nanjing University of Chinese MedicineSchool of Health Economics and Management, Nanjing University of Chinese MedicineSchool of Health Economics and Management, Nanjing University of Chinese MedicineSchool of Health Economics and Management, Nanjing University of Chinese MedicineSchool of First Clinical Medical, Nanjing University of Chinese MedicineJiangsu Research Center for Major Health Risk Management and TCM Control Policy, Nanjing University of Chinese MedicineSchool of Health Economics and Management, Nanjing University of Chinese MedicineAbstract Background Patient preferences have gradually been incorporated into decisions about cancer treatment regimens over recent years. Meanwhile, the efficacy of traditional Chinese medicine (TCM) in cancer-related treatments has been recognized. This study aimed to estimate the specific preferences of cancer patients for TCM treatment regimens to inform the clinical decision-making process for health promotion. Methods This cross-sectional investigation employed a discrete choice experiment (DCE) methodology to assess TCM treatment regimens preferences among cancer patients. The DCE systematically elicits participants’ preferences through the sequential presentation of hypothetical clinical scenarios with varying combinations of therapeutic attributes, with subsequent data analysis conducted using mixed logit models. We applied this methodology to examine cancer patient preferences regarding different TCM treatment regimens. Additionally, a subgroup analysis of sex groups was conducted to identify potential preference variations across demographic groups. Results In total, 728 participants completed the questionnaire and passed the consistency test. Control rate of disease, gastrointestinal adverse effects, mode of administration, treatment duration, quality of life, and monthly out-of-pocket cost had a significant impact on the TCM treatment preference of the participating cancer patients. Preferences almost remained consistent irrespective of the participants’ sex. Conclusions Differences in treatment have an impact on the preferences of TCM treatment in cancer patients. Cancer patients' preferences related to the control rate of disease and quality of life should be prioritized and considered in TCM treatment decision-making.https://doi.org/10.1186/s12906-025-04937-4Cancer patientTraditional Chinese medicine treatmentPreferencesDiscrete choice experiment
spellingShingle Jiao Zhang
Lihua Li
Huinan Xi
Qi Wang
Fan Jiang
Xin Sun
Xuebin Qiao
Aijun Xu
Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
BMC Complementary Medicine and Therapies
Cancer patient
Traditional Chinese medicine treatment
Preferences
Discrete choice experiment
title Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
title_full Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
title_fullStr Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
title_full_unstemmed Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
title_short Cancer patient preferences for traditional Chinese medicine treatment: a discrete choice experiment study
title_sort cancer patient preferences for traditional chinese medicine treatment a discrete choice experiment study
topic Cancer patient
Traditional Chinese medicine treatment
Preferences
Discrete choice experiment
url https://doi.org/10.1186/s12906-025-04937-4
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