Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances

As we humans continue our detrimental activities on the planet, the biodiversity loss is now seen as a big threat to entire ecosystem in which we all live. This issue becomes even more critical as we see a rapid increase in the number of animal species being listed as endangered, and a far greater r...

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Main Authors: Zhiqiang Han, Xin Liu, Haijun Wang, Izhar Hyder Qazi, Luyao Wang, Rui Du, Xiangpeng Dai, Chao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Veterinary Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1572150/full
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author Zhiqiang Han
Zhiqiang Han
Xin Liu
Haijun Wang
Izhar Hyder Qazi
Izhar Hyder Qazi
Luyao Wang
Luyao Wang
Rui Du
Xiangpeng Dai
Xiangpeng Dai
Chao Xu
author_facet Zhiqiang Han
Zhiqiang Han
Xin Liu
Haijun Wang
Izhar Hyder Qazi
Izhar Hyder Qazi
Luyao Wang
Luyao Wang
Rui Du
Xiangpeng Dai
Xiangpeng Dai
Chao Xu
author_sort Zhiqiang Han
collection DOAJ
description As we humans continue our detrimental activities on the planet, the biodiversity loss is now seen as a big threat to entire ecosystem in which we all live. This issue becomes even more critical as we see a rapid increase in the number of animal species being listed as endangered, and a far greater rate of species extinction. We all know that felines play a crucial part in our ecosystems, it is therefore safe to argue that their conservation could play an important role in minimizing the biodiversity loss. Advanced reproductive biotechnologies including testicular tissue cryopreservation and transplantation are considered as effective tools for the conservation of animal species. As we have seen with the Giant Panda, these biotechnologies could offer new possibilities for the conservation of other endangered species including felines. Although previously a few wild feline spp. were conserved by this method, little is known about the factors influencing the efficiency of these methods. Therefore, if we are to maximize the conservation efforts, further optimization of these biotechnologies is required to achieve better conservation results. In this article, we present an overview of testicular tissue of felines and the factors influencing testicular tissue cryopreservation and testicular graft recovery in felines.
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publisher Frontiers Media S.A.
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spelling doaj-art-d4302735a6ae453bbb65a8e01f53a8fc2025-08-20T03:08:31ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-04-011210.3389/fvets.2025.15721501572150Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advancesZhiqiang Han0Zhiqiang Han1Xin Liu2Haijun Wang3Izhar Hyder Qazi4Izhar Hyder Qazi5Luyao Wang6Luyao Wang7Rui Du8Xiangpeng Dai9Xiangpeng Dai10Chao Xu11College of Animal Science and Technology, Jilin Agricultural University, Changchun, ChinaInstitute of Zoology, Chinese Academy of Sciences, Beijing, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, ChinaJilin Province Northeast Tiger Garden and Jilin Wild Animal Rescue Breeding Center Committee, Changchun, ChinaGuangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, ChinaShaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, PakistanKey Laboratory of Organ Regeneration and Transplantation of Ministry of Education, First Hospital of Jilin University, Changchun, ChinaNational-Local Joint Engineering Laboratory of Animal Models for Human Disease, First Hospital, Jilin University, Changchun, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, ChinaKey Laboratory of Organ Regeneration and Transplantation of Ministry of Education, First Hospital of Jilin University, Changchun, ChinaNational-Local Joint Engineering Laboratory of Animal Models for Human Disease, First Hospital, Jilin University, Changchun, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, ChinaAs we humans continue our detrimental activities on the planet, the biodiversity loss is now seen as a big threat to entire ecosystem in which we all live. This issue becomes even more critical as we see a rapid increase in the number of animal species being listed as endangered, and a far greater rate of species extinction. We all know that felines play a crucial part in our ecosystems, it is therefore safe to argue that their conservation could play an important role in minimizing the biodiversity loss. Advanced reproductive biotechnologies including testicular tissue cryopreservation and transplantation are considered as effective tools for the conservation of animal species. As we have seen with the Giant Panda, these biotechnologies could offer new possibilities for the conservation of other endangered species including felines. Although previously a few wild feline spp. were conserved by this method, little is known about the factors influencing the efficiency of these methods. Therefore, if we are to maximize the conservation efforts, further optimization of these biotechnologies is required to achieve better conservation results. In this article, we present an overview of testicular tissue of felines and the factors influencing testicular tissue cryopreservation and testicular graft recovery in felines.https://www.frontiersin.org/articles/10.3389/fvets.2025.1572150/fullbig catsfertilitypreservationspermvitrification
spellingShingle Zhiqiang Han
Zhiqiang Han
Xin Liu
Haijun Wang
Izhar Hyder Qazi
Izhar Hyder Qazi
Luyao Wang
Luyao Wang
Rui Du
Xiangpeng Dai
Xiangpeng Dai
Chao Xu
Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
Frontiers in Veterinary Science
big cats
fertility
preservation
sperm
vitrification
title Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
title_full Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
title_fullStr Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
title_full_unstemmed Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
title_short Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
title_sort testicular tissue cryopreservation and transplantation as a strategy for feline conservation a review of research advances
topic big cats
fertility
preservation
sperm
vitrification
url https://www.frontiersin.org/articles/10.3389/fvets.2025.1572150/full
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