Improved Sensitivity in Comparative Genomic Hybridization Analysis of DNA Heteroploid Cell Mixtures after Pre-Enrichment of Subpopulations by Fluorescence Activated Cell Sorting

Improved Sensitivity in Comparative Genomic Hybridization Analysis of DNA Heteroploid Cell Mixtures after Pre-Enrichment of Subpopulations by Fluorescence Activated Cell Sorting

Cytogenetic analysis of solid tumors with comparative genomic hybridization (CGH) is hampered by the dilution of DNA from individual tumor subpopulations with DNA from other cells. We investigated to what extent this dilution effect can be alleviated using fluorescence activated cell sorting (flow s...

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Bibliographic Details
Main Authors: Jacob Larsen, Maria Kirchhoff, Hanne Rose, Tommy Gerdes, Jan Maahr, Claes Lundsteen, Jørgen K. Larsen
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/1999/149571
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