Alterations in the cecal microbiome of New Zealand White rabbits due to the long-acting anticoagulant rodenticide brodifacoum

Alterations in the cecal microbiome of New Zealand White rabbits due to the long-acting anticoagulant rodenticide brodifacoum

Introduction Long-acting anti-coagulant rodenticides (LAARs) are well characterized with respect to inhibition of vitamin K1 synthesis and effects on blood coagulation. However, effects of LAARs on the microbiome have not been explored.Methods We administered brodifacoum (BDF), one of the more poten...

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Bibliographic Details
Main Authors: Ankur Naqib, Intakhar Ahmad, Zachary McDonald, Sergey Kalinin, Jackie Rocha, Ankit Tandon, Ramanjaneyulu Rayala, Leonid Feferman, George E. Chlipala, Hui Chen, Matthew Lindeblad, Israel Rubinstein, Stefan J. Green, Richard B. van Breemen, Douglas L. Feinstein
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Toxicology Communications
Subjects:
Rodenticide
microbiome
rabbit
cecal
arginine
bile sequestrant
Online Access:https://www.tandfonline.com/doi/10.1080/24734306.2025.2500111
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