Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential
Abstract This study demonstrates the green synthesis of silver nanoparticles (AgNPs) using Hordeum vulgare seed extract, a natural polyphenol-rich reducing and stabilizing agent. The biosynthesized AgNPs were thoroughly characterized using UV-Vis spectroscopy, XRD, HRTEM, XPS, Zeta potential, DLS, T...
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Springer
2025-07-01
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| Series: | Discover Materials |
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| Online Access: | https://doi.org/10.1007/s43939-025-00342-3 |
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| author | Priya Gupta Hira Ilyas D. S. Raghav Sudha Tomar |
| author_facet | Priya Gupta Hira Ilyas D. S. Raghav Sudha Tomar |
| author_sort | Priya Gupta |
| collection | DOAJ |
| description | Abstract This study demonstrates the green synthesis of silver nanoparticles (AgNPs) using Hordeum vulgare seed extract, a natural polyphenol-rich reducing and stabilizing agent. The biosynthesized AgNPs were thoroughly characterized using UV-Vis spectroscopy, XRD, HRTEM, XPS, Zeta potential, DLS, TGA, FTIR, and FE-SEM. The XRD and HR-TEM characteristic confirm the particle size range of 10–30 nm. The UV-Vis spectra showed a surface plasmon resonance (SPR) peak between 400 and 450 nm, and XPS analysis confirmed the metallic nature of silver with distinct Ag 3d5/2 and Ag 3d3/2 peaks at 368.2 eV and 374.2 eV. A zeta potential of − 5.01 mV suggested moderate colloidal stability. The AgNPs displayed excellent catalytic efficiency in degrading Malachite Green dye, achieving over 95% degradation within 60 min at pH 8, following pseudo-first-order kinetics. The nanoparticles also retained catalytic activity over successive cycles, demonstrating strong recyclability and stability, making them suitable for environmental remediation. Furthermore, the AgNPs exhibited broad-spectrum antimicrobial activity against Escherichia coli, Bacillus subtilis, and Candida albicans. Antioxidant evaluation using the DPPH assay showed strong radical scavenging potential with an IC₅₀ value of 23.46 ± 0.04 µg/mL. Importantly, cytotoxicity assays against HCT-116 human colorectal cancer cells revealed a potent anticancer effect with an IC₅₀ of 4.61 µg/mL. |
| format | Article |
| id | doaj-art-d41d141a0691484599f96602e168fdd5 |
| institution | Kabale University |
| issn | 2730-7727 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Springer |
| record_format | Article |
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| spelling | doaj-art-d41d141a0691484599f96602e168fdd52025-08-20T04:03:11ZengSpringerDiscover Materials2730-77272025-07-015112710.1007/s43939-025-00342-3Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potentialPriya Gupta0Hira Ilyas1D. S. Raghav2Sudha Tomar3Department of Applied Science & Humanities, Invertis University BareillyDepartment of Applied Science & Humanities, Invertis University BareillyDepartment of Applied Science & Humanities, Invertis University BareillyDepartment of Applied Science & Humanities, Invertis University BareillyAbstract This study demonstrates the green synthesis of silver nanoparticles (AgNPs) using Hordeum vulgare seed extract, a natural polyphenol-rich reducing and stabilizing agent. The biosynthesized AgNPs were thoroughly characterized using UV-Vis spectroscopy, XRD, HRTEM, XPS, Zeta potential, DLS, TGA, FTIR, and FE-SEM. The XRD and HR-TEM characteristic confirm the particle size range of 10–30 nm. The UV-Vis spectra showed a surface plasmon resonance (SPR) peak between 400 and 450 nm, and XPS analysis confirmed the metallic nature of silver with distinct Ag 3d5/2 and Ag 3d3/2 peaks at 368.2 eV and 374.2 eV. A zeta potential of − 5.01 mV suggested moderate colloidal stability. The AgNPs displayed excellent catalytic efficiency in degrading Malachite Green dye, achieving over 95% degradation within 60 min at pH 8, following pseudo-first-order kinetics. The nanoparticles also retained catalytic activity over successive cycles, demonstrating strong recyclability and stability, making them suitable for environmental remediation. Furthermore, the AgNPs exhibited broad-spectrum antimicrobial activity against Escherichia coli, Bacillus subtilis, and Candida albicans. Antioxidant evaluation using the DPPH assay showed strong radical scavenging potential with an IC₅₀ value of 23.46 ± 0.04 µg/mL. Importantly, cytotoxicity assays against HCT-116 human colorectal cancer cells revealed a potent anticancer effect with an IC₅₀ of 4.61 µg/mL.https://doi.org/10.1007/s43939-025-00342-3Hordeum vulgareSilver nanoparticlesAntioxidantAntimicrobialAnd green synthesis |
| spellingShingle | Priya Gupta Hira Ilyas D. S. Raghav Sudha Tomar Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential Discover Materials Hordeum vulgare Silver nanoparticles Antioxidant Antimicrobial And green synthesis |
| title | Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential |
| title_full | Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential |
| title_fullStr | Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential |
| title_full_unstemmed | Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential |
| title_short | Sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract: catalysis, antioxidant, anti-cancerous and antimicrobial potential |
| title_sort | sustainable synthesis of silver nanoparticles via hordeum vulgare seed extract catalysis antioxidant anti cancerous and antimicrobial potential |
| topic | Hordeum vulgare Silver nanoparticles Antioxidant Antimicrobial And green synthesis |
| url | https://doi.org/10.1007/s43939-025-00342-3 |
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