Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient
We report a female patient with rheumatoid arthritis which was refractory to methotrexate, leflunomide, and anti-TNF therapy. She was treated with anti-IL-6 tocilizumab (TCZ), with an early appearance of sterile pustules on erythematous swollen skin of trunk, back, and abdominal area. The lesions we...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2012/517424 |
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| author | J. H. Izquierdo F. Bonilla-Abadía C. D. Ochoa A. Agualimpia G. J. Tobón C. A. Cañas |
| author_facet | J. H. Izquierdo F. Bonilla-Abadía C. D. Ochoa A. Agualimpia G. J. Tobón C. A. Cañas |
| author_sort | J. H. Izquierdo |
| collection | DOAJ |
| description | We report a female patient with rheumatoid arthritis which was refractory to methotrexate, leflunomide, and anti-TNF therapy. She was treated with anti-IL-6 tocilizumab (TCZ), with an early appearance of sterile pustules on erythematous swollen skin of trunk, back, and abdominal area. The lesions were consistent with the diagnosis of acute drug-related generalized exanthematous pustulosis (AGEP). This adverse event was controlled with medical treatment without requiring removal of TCZ. |
| format | Article |
| id | doaj-art-d418df4bfaf1487ab1baa2cd66b294be |
| institution | OA Journals |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-d418df4bfaf1487ab1baa2cd66b294be2025-08-20T02:19:45ZengWileyCase Reports in Rheumatology2090-68892090-68972012-01-01201210.1155/2012/517424517424Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis PatientJ. H. Izquierdo0F. Bonilla-Abadía1C. D. Ochoa2A. Agualimpia3G. J. Tobón4C. A. Cañas5Rheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaRheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaRheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaRheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaRheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaRheumatology Unit, Valle del Lili Foundation, ICESI University, Cali, ColombiaWe report a female patient with rheumatoid arthritis which was refractory to methotrexate, leflunomide, and anti-TNF therapy. She was treated with anti-IL-6 tocilizumab (TCZ), with an early appearance of sterile pustules on erythematous swollen skin of trunk, back, and abdominal area. The lesions were consistent with the diagnosis of acute drug-related generalized exanthematous pustulosis (AGEP). This adverse event was controlled with medical treatment without requiring removal of TCZ.http://dx.doi.org/10.1155/2012/517424 |
| spellingShingle | J. H. Izquierdo F. Bonilla-Abadía C. D. Ochoa A. Agualimpia G. J. Tobón C. A. Cañas Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient Case Reports in Rheumatology |
| title | Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient |
| title_full | Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient |
| title_fullStr | Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient |
| title_full_unstemmed | Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient |
| title_short | Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient |
| title_sort | acute generalized exanthematous pustulosis due to tocilizumab in a rheumatoid arthritis patient |
| url | http://dx.doi.org/10.1155/2012/517424 |
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