Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty

ObjectiveThis study aims to explore the clinical efficacy and safety of a urethroplasty technique for fossa navicularis (FN) strictures using a transurethral annular inlay oral mucosa graft.MethodsA retrospective analysis was conducted on clinical data from patients with urethral meatus and navicula...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhenyu Li, Zhiguang Zhao, Geng Zhang, He Wang, Bo Zhang, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Reproductive Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frph.2025.1555597/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849243430760218624
author Zhenyu Li
Zhiguang Zhao
Geng Zhang
He Wang
Bo Zhang
Wei Zhang
author_facet Zhenyu Li
Zhiguang Zhao
Geng Zhang
He Wang
Bo Zhang
Wei Zhang
author_sort Zhenyu Li
collection DOAJ
description ObjectiveThis study aims to explore the clinical efficacy and safety of a urethroplasty technique for fossa navicularis (FN) strictures using a transurethral annular inlay oral mucosa graft.MethodsA retrospective analysis was conducted on clinical data from patients with urethral meatus and navicular fossa stricture who underwent transurethral reconstruction using annular inlay oral mucosa graft urethroplasty in Tangdu Hospital from July 2021 to October 2024. Operation success was defined as the ability to pass the F24 urethral probe, and the secondary outcome is the urinary flow rate and patient satisfaction at 1, 3, 6, and 12 months.ResultsAll 12 patients successfully completed the surgery. The average age was 56.8 ± 6.8 years, and the average length of urethral stricture was 1.6 ± 0.2 cm. Three patients had a history of transurethral endoscopic surgery, eight had penile lichen sclerosus (LS), and one had no obvious causes. Over a median follow-up of 19 months, the average maximum urinary flow rate was 21.2 ± 3.2 ml/s at 3 months, and the average maximum urinary flow rate was 19.5 ± 4.2 ml/s at 12 months. One patient experienced urine pain with a thin stream and spraying urination after 3 months. Physical examination of the urethral meatus opening scar was found, and the symptoms disappeared after urethral incision. The follow-up survey of sexual life after 1 year showed that seven patients (58.3%) had successful life within 1 year compared with two patients (16.7%) before surgery. There were no cases of erectile dysfunction and poor wound healing. The patients were either very satisfied (75%) or satisfied (25%) with the operation. All patients would recommend urethroplasty to others.ConclusionTransurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect on the penile head. This technique has advantages in improving sexual function and better penile head cosmesis.
format Article
id doaj-art-d4156d09bb6d4feea29ad94b936396ee
institution Kabale University
issn 2673-3153
language English
publishDate 2025-08-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Reproductive Health
spelling doaj-art-d4156d09bb6d4feea29ad94b936396ee2025-08-20T03:59:30ZengFrontiers Media S.A.Frontiers in Reproductive Health2673-31532025-08-01710.3389/frph.2025.15555971555597Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplastyZhenyu LiZhiguang ZhaoGeng ZhangHe WangBo ZhangWei ZhangObjectiveThis study aims to explore the clinical efficacy and safety of a urethroplasty technique for fossa navicularis (FN) strictures using a transurethral annular inlay oral mucosa graft.MethodsA retrospective analysis was conducted on clinical data from patients with urethral meatus and navicular fossa stricture who underwent transurethral reconstruction using annular inlay oral mucosa graft urethroplasty in Tangdu Hospital from July 2021 to October 2024. Operation success was defined as the ability to pass the F24 urethral probe, and the secondary outcome is the urinary flow rate and patient satisfaction at 1, 3, 6, and 12 months.ResultsAll 12 patients successfully completed the surgery. The average age was 56.8 ± 6.8 years, and the average length of urethral stricture was 1.6 ± 0.2 cm. Three patients had a history of transurethral endoscopic surgery, eight had penile lichen sclerosus (LS), and one had no obvious causes. Over a median follow-up of 19 months, the average maximum urinary flow rate was 21.2 ± 3.2 ml/s at 3 months, and the average maximum urinary flow rate was 19.5 ± 4.2 ml/s at 12 months. One patient experienced urine pain with a thin stream and spraying urination after 3 months. Physical examination of the urethral meatus opening scar was found, and the symptoms disappeared after urethral incision. The follow-up survey of sexual life after 1 year showed that seven patients (58.3%) had successful life within 1 year compared with two patients (16.7%) before surgery. There were no cases of erectile dysfunction and poor wound healing. The patients were either very satisfied (75%) or satisfied (25%) with the operation. All patients would recommend urethroplasty to others.ConclusionTransurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect on the penile head. This technique has advantages in improving sexual function and better penile head cosmesis.https://www.frontiersin.org/articles/10.3389/frph.2025.1555597/fullurethral stricturenavicular fossaoral mucosaurethroplastyannular inlay
spellingShingle Zhenyu Li
Zhiguang Zhao
Geng Zhang
He Wang
Bo Zhang
Wei Zhang
Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
Frontiers in Reproductive Health
urethral stricture
navicular fossa
oral mucosa
urethroplasty
annular inlay
title Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
title_full Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
title_fullStr Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
title_full_unstemmed Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
title_short Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
title_sort clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty
topic urethral stricture
navicular fossa
oral mucosa
urethroplasty
annular inlay
url https://www.frontiersin.org/articles/10.3389/frph.2025.1555597/full
work_keys_str_mv AT zhenyuli clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty
AT zhiguangzhao clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty
AT gengzhang clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty
AT hewang clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty
AT bozhang clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty
AT weizhang clinicalobservationoftransurethralreconstructionofurethralmeatusandnavicularisfossashortstrictureswithannularinlayoralmucosagrafturethroplasty