The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study
Abstract Objectives Mayo adhesive probability (MAP) score affects the outcomes of adrenaletomy. Aimed to determine whether the modified retroperitoneal laparoscopic adrenalectomy (MRLA) overcomes periadrenal fat adhesion compared to Classical retroperitoneal laparoscopic adrenalectomy (CRLA) to achi...
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BMC
2025-05-01
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| Series: | BMC Urology |
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| Online Access: | https://doi.org/10.1186/s12894-025-01809-4 |
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| author | Minxiong Hu Wenchao Cai Yupeng Chen Xiao Xu Yangbiao Wu Yangpeng Lian Qingguo Zhu Liefu Ye |
| author_facet | Minxiong Hu Wenchao Cai Yupeng Chen Xiao Xu Yangbiao Wu Yangpeng Lian Qingguo Zhu Liefu Ye |
| author_sort | Minxiong Hu |
| collection | DOAJ |
| description | Abstract Objectives Mayo adhesive probability (MAP) score affects the outcomes of adrenaletomy. Aimed to determine whether the modified retroperitoneal laparoscopic adrenalectomy (MRLA) overcomes periadrenal fat adhesion compared to Classical retroperitoneal laparoscopic adrenalectomy (CRLA) to achieve better surgical outcomes. Patients and methods Patients admitted from January 2016 to December 2022 were retrospectively analyzed and systematically categorized into two distinct cohorts: the MRLA group and the CRLA group, based on specific criteria.The main surgical techniques modified of MRLA is third separation level: between the edge of adrenal gland and the peripheral renal fat. The baseline characteristics and perioperative data, e.g., age, gender, BMI, tumor position, tumor size (cm), MAP score, P distance (cm), perinephric stranding, and periadrenal stranding, estimated blood loss, Operating time, were analyzed, with statistical significance defined as p < 0.05. We analyzed the differences between groups using the t test. For measurement data that didn’t follow normal distribution, we described the concentration and dispersion trended using M (Q25, Q75) and analyzed the differences between groups using the M-U test. For data that met certain conditions like being linear, normal and independent, we used linear regression analysis. For binary classification of dependent variables, we used binary logistic regression analysis. Results A total of 731 patients underwent adrenaletomy, and 651 patients had adequate data, were available for MAP score assessment. Of these patients, 247 were in the MRLA group, whereas 404 were in the CRLA group, baseline characteristics weren’t found to be different between the two groups (p > 0.05). The MRLA group exhibited superior outcomes in terms of operating time, duration, postoperative hospital stay, estimated blood loss, and complications, in comparison to the CRLA group. Further analysis revealed that periadrenal stranding could be the underlying cause for this discrepancy. Conclusions The MRLA effectively overcame the impact of adhesive periadrenal fat (APAF) compared to CRLA. We recommend to employ the MRLA for patients with preoperative CT images indicating periadrenal fat adhesion. |
| format | Article |
| id | doaj-art-d410e83e6f564bed80352e37ab6f71ce |
| institution | Kabale University |
| issn | 1471-2490 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj-art-d410e83e6f564bed80352e37ab6f71ce2025-08-24T11:53:02ZengBMCBMC Urology1471-24902025-05-012511810.1186/s12894-025-01809-4The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective studyMinxiong Hu0Wenchao Cai1Yupeng Chen2Xiao Xu3Yangbiao Wu4Yangpeng Lian5Qingguo Zhu6Liefu Ye7Shengli Clinical College of Fujian Medical UniversityShengli Clinical College of Fujian Medical UniversityFujian Medical UniversityFuzhou University Affiliated Provincial HospitalFujian Medical UniversityCenter for Information Management, Fujian Provincial HospitalShengli Clinical College of Fujian Medical UniversityShengli Clinical College of Fujian Medical UniversityAbstract Objectives Mayo adhesive probability (MAP) score affects the outcomes of adrenaletomy. Aimed to determine whether the modified retroperitoneal laparoscopic adrenalectomy (MRLA) overcomes periadrenal fat adhesion compared to Classical retroperitoneal laparoscopic adrenalectomy (CRLA) to achieve better surgical outcomes. Patients and methods Patients admitted from January 2016 to December 2022 were retrospectively analyzed and systematically categorized into two distinct cohorts: the MRLA group and the CRLA group, based on specific criteria.The main surgical techniques modified of MRLA is third separation level: between the edge of adrenal gland and the peripheral renal fat. The baseline characteristics and perioperative data, e.g., age, gender, BMI, tumor position, tumor size (cm), MAP score, P distance (cm), perinephric stranding, and periadrenal stranding, estimated blood loss, Operating time, were analyzed, with statistical significance defined as p < 0.05. We analyzed the differences between groups using the t test. For measurement data that didn’t follow normal distribution, we described the concentration and dispersion trended using M (Q25, Q75) and analyzed the differences between groups using the M-U test. For data that met certain conditions like being linear, normal and independent, we used linear regression analysis. For binary classification of dependent variables, we used binary logistic regression analysis. Results A total of 731 patients underwent adrenaletomy, and 651 patients had adequate data, were available for MAP score assessment. Of these patients, 247 were in the MRLA group, whereas 404 were in the CRLA group, baseline characteristics weren’t found to be different between the two groups (p > 0.05). The MRLA group exhibited superior outcomes in terms of operating time, duration, postoperative hospital stay, estimated blood loss, and complications, in comparison to the CRLA group. Further analysis revealed that periadrenal stranding could be the underlying cause for this discrepancy. Conclusions The MRLA effectively overcame the impact of adhesive periadrenal fat (APAF) compared to CRLA. We recommend to employ the MRLA for patients with preoperative CT images indicating periadrenal fat adhesion.https://doi.org/10.1186/s12894-025-01809-4Laparoscopic adrenalectomyAdhesive perinephric fatAdhesive periadrenal fatMayo adhesive probability scoreBMI |
| spellingShingle | Minxiong Hu Wenchao Cai Yupeng Chen Xiao Xu Yangbiao Wu Yangpeng Lian Qingguo Zhu Liefu Ye The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study BMC Urology Laparoscopic adrenalectomy Adhesive perinephric fat Adhesive periadrenal fat Mayo adhesive probability score BMI |
| title | The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study |
| title_full | The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study |
| title_fullStr | The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study |
| title_full_unstemmed | The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study |
| title_short | The modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach: a retrospective study |
| title_sort | modified retroperitoneal laparoscopic adrenalectomy overcomes adhesive periadrenal fat and achieves superior outcomes than classical approach a retrospective study |
| topic | Laparoscopic adrenalectomy Adhesive perinephric fat Adhesive periadrenal fat Mayo adhesive probability score BMI |
| url | https://doi.org/10.1186/s12894-025-01809-4 |
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