Comprehensive Evaluation of Neuroprotective Effects of Levetiracetam in C57BL/6J Male Mice Model of Parkinsonism: Preclinical Insights

Comprehensive Evaluation of Neuroprotective Effects of Levetiracetam in C57BL/6J Male Mice Model of Parkinsonism: Preclinical Insights

Introduction: Levetiracetam (LEV), an anticonvulsant used for epilepsy, exhibits neuroprotective effects by stabilising neuronal activity and reducing excitotoxicity. Parkinsonism, caused by the degeneration of dopaminergic neurons, is primarily managed symptomatically. LEV may offer both symptom re...

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Bibliographic Details
Main Authors: Neeraj Pandey, VP Karthik, Preetha Selva, Philo Hazeena
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2025-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
antioxidant
dopaminergic neurons
1-methyl-4-phenyl-1
2
3
6-tetrahydropyridine
neurodegenerative
Online Access:https://jcdr.net/articles/PDF/21141/78708_CE[Ra1]__F(KR)_QC(AN_SS)_PF1(Rf_OM)_PFA(IS)_PB(Rf_IS)_PN(IS).pdf
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