MAAT: a new nonparametric Bayesian framework for incorporating multiple functional annotations in transcriptome-wide association studies
Abstract Transcriptome-wide association study (TWAS) has emerged as a powerful tool for translating the myriad variations identified by genome-wide association studies (GWAS) into regulated genes in the post-GWAS era. While integrating annotation information has been shown to enhance power, current...
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Main Authors: | Han Wang, Xiang Li, Teng Li, Zhe Li, Pak Chung Sham, Yan Dora Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-025-03485-x |
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