The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.

<h4>Introduction</h4>Generalized anxiety disorder (GAD) is the most common type of anxiety disorders. GAD usually occurs in adolescence or early adulthood, and the prevalence of GAD is higher among college-enrolled young adults than in the general adult population. However, there is a la...

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Main Authors: Yang Wang, Xinbo Gu, Baohua Zhi, Yan Yan, Fengyan Lu, Hantong Hu, Quanai Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316804
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author Yang Wang
Xinbo Gu
Baohua Zhi
Yan Yan
Fengyan Lu
Hantong Hu
Quanai Zhang
author_facet Yang Wang
Xinbo Gu
Baohua Zhi
Yan Yan
Fengyan Lu
Hantong Hu
Quanai Zhang
author_sort Yang Wang
collection DOAJ
description <h4>Introduction</h4>Generalized anxiety disorder (GAD) is the most common type of anxiety disorders. GAD usually occurs in adolescence or early adulthood, and the prevalence of GAD is higher among college-enrolled young adults than in the general adult population. However, there is a lack of evidence regarding the effectiveness of acupuncture in the treatment of GAD. This study's objective is to evaluate the efficacy of acupuncture in the treatment of GAD in college students and its stability.<h4>Methods</h4>A total of 142 subjects will be recruited for the randomized controlled trial (RCT) of current undergraduate and graduate students with GAD and will be randomized into treatment and control groups. The treatment group will receive conventional acupuncture, while the control group will receive sham acupuncture using Streitberger needles. Both groups will be administered 8 acupuncture treatment (2 times per week for 4 weeks). The follow-up duration will be 2 months. The Hamilton Anxiety Scale (HAMA) will be used as the primary outcome of the study to measure the severity of anxiety disorder. The secondary outcomes of this study will be included the Pittsburgh Sleep Quality Index (PSQI) and Self-rating anxiety Scale (SAS). The study will also evaluate the success of blinding and the safety.<h4>Discussions</h4>Findings of this RCT will help evaluate the efficacy of acupuncture treatment for GAD in college students, potentially promoting it as an alternative treatment option. The protocol was registered at clinicaltrials.gov (Identifier: ChiCTR2400080688).
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spelling doaj-art-d3fe5488a421421db09eeac20e681fa22025-01-21T05:31:21ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031680410.1371/journal.pone.0316804The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.Yang WangXinbo GuBaohua ZhiYan YanFengyan LuHantong HuQuanai Zhang<h4>Introduction</h4>Generalized anxiety disorder (GAD) is the most common type of anxiety disorders. GAD usually occurs in adolescence or early adulthood, and the prevalence of GAD is higher among college-enrolled young adults than in the general adult population. However, there is a lack of evidence regarding the effectiveness of acupuncture in the treatment of GAD. This study's objective is to evaluate the efficacy of acupuncture in the treatment of GAD in college students and its stability.<h4>Methods</h4>A total of 142 subjects will be recruited for the randomized controlled trial (RCT) of current undergraduate and graduate students with GAD and will be randomized into treatment and control groups. The treatment group will receive conventional acupuncture, while the control group will receive sham acupuncture using Streitberger needles. Both groups will be administered 8 acupuncture treatment (2 times per week for 4 weeks). The follow-up duration will be 2 months. The Hamilton Anxiety Scale (HAMA) will be used as the primary outcome of the study to measure the severity of anxiety disorder. The secondary outcomes of this study will be included the Pittsburgh Sleep Quality Index (PSQI) and Self-rating anxiety Scale (SAS). The study will also evaluate the success of blinding and the safety.<h4>Discussions</h4>Findings of this RCT will help evaluate the efficacy of acupuncture treatment for GAD in college students, potentially promoting it as an alternative treatment option. The protocol was registered at clinicaltrials.gov (Identifier: ChiCTR2400080688).https://doi.org/10.1371/journal.pone.0316804
spellingShingle Yang Wang
Xinbo Gu
Baohua Zhi
Yan Yan
Fengyan Lu
Hantong Hu
Quanai Zhang
The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
PLoS ONE
title The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
title_full The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
title_fullStr The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
title_full_unstemmed The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
title_short The efficacy of acupuncture for generalized anxiety disorder (GAD) in college students: Study protocol for a randomized controlled trial.
title_sort efficacy of acupuncture for generalized anxiety disorder gad in college students study protocol for a randomized controlled trial
url https://doi.org/10.1371/journal.pone.0316804
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