Progress in Accelerator Production of Important Medical Isotopes
With the rapid development of nuclear science and technology，medical radioisotopes play an increasingly important role in nuclear medicine，and are widely used in the diagnosis and treatment of cardiovascular and cerebrovascular diseases，tumors and other diseases. Accelerator production of medical ra...
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| Format: | Article |
| Language: | zho |
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Editorial Board of Journal of Isotopes
2024-12-01
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| Series: | Journal of Isotopes |
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| Online Access: | https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.100 |
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| author | Shizhong AN Guoying GUAN Yunlong ZHAO Zhe WANG Yong LI Yu WANG Pengfei ZHAO Guofang SONG Guobao WANG |
| author_facet | Shizhong AN Guoying GUAN Yunlong ZHAO Zhe WANG Yong LI Yu WANG Pengfei ZHAO Guofang SONG Guobao WANG |
| author_sort | Shizhong AN |
| collection | DOAJ |
| description | With the rapid development of nuclear science and technology，medical radioisotopes play an increasingly important role in nuclear medicine，and are widely used in the diagnosis and treatment of cardiovascular and cerebrovascular diseases，tumors and other diseases. Accelerator production of medical radioisotopes has the advantages of flexibility，efficiency，system safety and high nuclide activity，and is one of the important production methods to ensure the safe and stable supply of medical radioisotopes. In 2021，China Atomic Energy Authority together with seven other ministries，jointly released the “Medium - and Long Term Development Plan for Medical Isotopes (2021−2035)”，which clarifies that there are 14 important medical isotopes that China needs to focus on developing before 2035，of which 9 isotopes can be produced by accelerators. This article mainly introduces the production and application overview of accelerators for the 9 important medical isotopes listed in the plan. The 9 important medical isotopes include the imaging nuclides 123I，124I，64Cu，68Ga，89Zr and the therapeutic nuclides 186Re，103Pd，225Ac ,223Ra .Among them,225Ac、68Ge and 223Ra are the focus of isotope production in medium and high energy accelerators，and also are the main development trend of accelerator production radioisotopes. This study provides a comprehensive review of the nuclear properties，applications，reaction cross-sections，yields，and production methods of the diagnostic and therapeutic nuclides mentioned above，providing reference for the production of related nuclides. |
| format | Article |
| id | doaj-art-d3faf873b09e40be9b07ac50d3c410d8 |
| institution | Kabale University |
| issn | 1000-7512 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Board of Journal of Isotopes |
| record_format | Article |
| series | Journal of Isotopes |
| spelling | doaj-art-d3faf873b09e40be9b07ac50d3c410d82025-01-02T02:07:43ZzhoEditorial Board of Journal of IsotopesJournal of Isotopes1000-75122024-12-0137650752010.7538/tws.2024.youxian.100202410100Progress in Accelerator Production of Important Medical IsotopesShizhong AN0Guoying GUAN1Yunlong ZHAO2Zhe WANG3Yong LI4Yu WANG5Pengfei ZHAO6Guofang SONG7Guobao WANG8China Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaChina Institute of Atomic Energy, Beijing 102413, ChinaWith the rapid development of nuclear science and technology，medical radioisotopes play an increasingly important role in nuclear medicine，and are widely used in the diagnosis and treatment of cardiovascular and cerebrovascular diseases，tumors and other diseases. Accelerator production of medical radioisotopes has the advantages of flexibility，efficiency，system safety and high nuclide activity，and is one of the important production methods to ensure the safe and stable supply of medical radioisotopes. In 2021，China Atomic Energy Authority together with seven other ministries，jointly released the “Medium - and Long Term Development Plan for Medical Isotopes (2021−2035)”，which clarifies that there are 14 important medical isotopes that China needs to focus on developing before 2035，of which 9 isotopes can be produced by accelerators. This article mainly introduces the production and application overview of accelerators for the 9 important medical isotopes listed in the plan. The 9 important medical isotopes include the imaging nuclides 123I，124I，64Cu，68Ga，89Zr and the therapeutic nuclides 186Re，103Pd，225Ac ,223Ra .Among them,225Ac、68Ge and 223Ra are the focus of isotope production in medium and high energy accelerators，and also are the main development trend of accelerator production radioisotopes. This study provides a comprehensive review of the nuclear properties，applications，reaction cross-sections，yields，and production methods of the diagnostic and therapeutic nuclides mentioned above，providing reference for the production of related nuclides.https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.100acceleratormedical isotope productionimaging nuclidestherapeutic nuclides |
| spellingShingle | Shizhong AN Guoying GUAN Yunlong ZHAO Zhe WANG Yong LI Yu WANG Pengfei ZHAO Guofang SONG Guobao WANG Progress in Accelerator Production of Important Medical Isotopes Journal of Isotopes accelerator medical isotope production imaging nuclides therapeutic nuclides |
| title | Progress in Accelerator Production of Important Medical Isotopes |
| title_full | Progress in Accelerator Production of Important Medical Isotopes |
| title_fullStr | Progress in Accelerator Production of Important Medical Isotopes |
| title_full_unstemmed | Progress in Accelerator Production of Important Medical Isotopes |
| title_short | Progress in Accelerator Production of Important Medical Isotopes |
| title_sort | progress in accelerator production of important medical isotopes |
| topic | accelerator medical isotope production imaging nuclides therapeutic nuclides |
| url | https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.100 |
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